Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
HIV incidence and compliance with deferral criteria over three progressively shorter time deferrals for men who have sex with men in Canada Caffrey N, Goldman M, Osmond L, Yi Q-L, Fan W, O'Brien SF 2022 Transfusion View Regulators MSM research
Transfusion thresholds in myelodysplastic syndrome - Helping patients live better Balitsky A, Arnold D 2022 Transfusion View Health care providers Clinical research
KEL1 negative red cell transfusions for females of current or future child-bearing potential: A clinical impact and feasibility study Ning S, Morin PA, Elahie A, Li N, Liu Y, Barty R, Clarke G, Zeller M, Heddle NM 2023 Transfusion View Health care providers Clinical research
An epidemiologic cohort study reviewing the practice of blood product transfusions among a population of pediatric oncology patients Lieberman L, Liu Y, Portwine C, Barty RL, Heddle NM 2014 Transfusion View Health care providers Clinical research
Enhanced Pathogenicity of biofilm-negative Staphylococcus epidermidis isolated from platelet preparations Hodgson SD, Greco-Stewart V, Jimenez CS, Sifri CD, Brassinga AKC, Ramirez-Arcos S 2014 Transfusion View Blood operators Basic research
Platelet transfusion reactions do not occur more often in recipients transfused with apheresis versus buffy coat platelet concentrates Cserti-Gazdewich C, Escorcia A, Pendergrast J, Lieberman L, Skeate R, Lin Y, Callum J 2016 Transfusion View Researchers Clinical research
Rituximab maintenance for relapsed refractory thrombotic thrombocytopenic purpura Bhagirath VC, Kelton JG, Moore J, Arnold DM 2012 Transfusion View Health care providers Clinical research
Stability of relevant plasma protein activities in cryosupernatant plasma units during refrigerated storage for up to 5 days postthaw Bhakta V, Jenkins C, Ramirez-Arcos S, Sheffield WP 2014 Transfusion View Blood operators New or improved product or process
Validation and implementation of a new hemoglobinometer for donor screening at Canadian Blood Services Goldman M, Uzicanin S, Yi QL, Acker JP, Ramirez-Arcos S 2012 Transfusion View Blood operators New or improved product or process
Compliance with time-based deferrals for men who have sex with men O'Brien SF, Osmond L, Fan W, Yi Q-L, Goldman M 2019 Transfusion View Researchers MSM research
Cold-stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality Schubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K 2021 Transfusion View Researchers New or improved product or process
Why We Swab: A library of stories in stem cell donation Jagelaviciute G, Kum E, Li EW, Rosenfeld A, Williams K, Kandel R, DeGurse N, Park B, Okonofua S, Sano L, Gerofsky M, Sharp A, Hatkar R, Thyagu S, Fingrut WB 2022 Transfusion View Health care providers Ethical, legal & social implications research
Comparison of donor and general population demographics over time: a BEST collaborative group study Goldman M, Steele WR, Di Angelantonio E, van den Hurk K, Vassallo RR, Germain M, O'Brien SF 2017 Transfusion View Blood operators Clinical research
Septic transfusion case caused by a platelet pool with visible clotting due to contamination with Staphylococcus aureus Loza-Correa M, Kou Y, Taha M, Kalab M, Ronholm J, Schlievert PM, Cahill MP, Skeate R, Cserti-Gazdewich C, Ramirez-Arcos S 2017 Transfusion View Health care providers Clinical research
Critical developments of 2018: A review of the literature from selected topics in transfusion. A committee report from the AABB's Clinical Transfusion Medicine Committee Cohn CS, Allen ES, Cushing MM, Dunbar NM, Friedman DF, Goel R, Harm SK, Heddle N, Hopkins CK, Klapper E, Perumbeti A, Ramsey G, Raval JS, Schwartz J, Shaz BH, Spinella PC, Pagano MB 2019 Transfusion View Researchers Clinical research
A retrospective study of the added value of parallel titers compared with serial titers Lin Y, Cohen R, Buckstein J, Callum J, Lieberman L 2019 Transfusion View Health care providers Clinical research
Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV 2021 Transfusion View Researchers Basic research
Blood shortages planning in Canada: The National Emergency Blood Management Committee experience during the first 6 months of the COVID-19 pandemic Prokopchuk-Gauk O, Petraszko T, Nahirniak S, Doncaster C, Levy I 2021 Transfusion View Regulators Benchmarking and standard setting
Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men Castillo G, Vesnaver E, Gibson E, Butler-Foster T, Goldman M, Hill NE, Rosser A, Lapierre D, Rubini KA, MacDonagh R, Miguel G, Palumbo A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Bridel W, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J 2022 Transfusion View Blood operators MSM research
AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections AABB Clinical Transfusion Medicine Committee, Heddle NM, Boeckh M, Grossman B, Jacobson J, Kleinman S, Tobian AAR, Webert K, Wong ECC, Roback JD 2016 Transfusion View Blood operators Clinical research
Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures van der Meer PF, Cancelas JA, Cardigan R, Devine DV, Gulliksson H, Sparrow RL, Vassallo RR, de Wildt-Eggen J, Baumann-Baretti B, Hess JR, for the BC 2011 Transfusion View Blood operators New or improved product or process
In vitro platelet quality in storage containers used for pediatric transfusions Weiss S, Scammell K, Levin E, Culibrk B, Zolfaghari S, Gyongyossy-Issa MI, Acker JP 2012 Transfusion View Health care providers New or improved product or process
Iron deficiency in Canadian blood donors Goldman M, Uzicanin S, Scalia V, O'Brien SF 2014 Transfusion View Health care providers Clinical research
Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP 2017 Transfusion View Researchers Basic research
Platelet concentrates from fresh or overnight-stored blood, an international study Dijkstra-Tiekstra MJ, van der Meer PF, Cardigan R, Devine D, Prowse C, Sandgren P, de Wildt-Eggen J, for the Biomedical Excellence for Safer Transfusion C 2011 Transfusion View Blood operators New or improved product or process
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J 2017 Cell Rep View Researchers Basic research
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory Yudin J, Heddle NM 2014 Lab Med View Health care providers Clinical research
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP 2023 Sci Rep View Researchers Basic research
IVIG regulates the survival of human but not mouse neutrophils Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S 2017 Sci Rep View Researchers Basic research
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP 2017 Sci Rep View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H 2017 Sci Rep View Researchers New or improved product or process
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR 2011 Viral Immunol View Researchers Basic research
T cell-mediated autoimmunity in immune thrombocytopenia Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM 2022 Eur J Haematol View Researchers Clinical research
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG 2015 Eur J Haematol View Researchers Clinical research
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM 2013 Eur J Haematol View Health care providers Clinical research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N 2017 Eur J Haematol View Researchers Basic research