Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Acquired Thrombocytopenia Warkentin TE, Mithoowani S, Arnold DM 2019 Concise Guide to Hematology View Other Other
Assessing the Threat: Public Concern Wiles A, Bennett JL, Devine D 2019 Blood Safety : A Guide to Monitoring and Responding to Potential New Threats View Other Benchmarking and standard setting
Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics Yang X, Kang N, Toyofuku WM, Scott MD 2018 Immunobiology View Researchers Basic research
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E 2018 PNAS View Researchers Basic research
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression Huard CC, Tremblay CS, Magron A, Levesque G, Carreau M 2014 PNAS View Researchers Basic research
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS View Researchers Basic research
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, O'Loughlin KG, Shackleford DM, Justino de Almeida M, Carrillo AK, Clark JA, Dennis AS, Diep J, Deng X, Duffy S, Endsley AN, Fedewa G, Guiguemde WA, Gomez MG, Holbrook G, Horst J, Kim CC, Liu J, Lee MC, Matheny A, Martinez MS, Miller G, Rodriguez-Alejandre A, Sanz L, Sigal M, Spillman NJ, Stein PD, Wang Z, Zhu F, Waterson D, Knapp S, Shelat A, Avery VM, Fidock DA, Gamo FJ, Charman SA, Mirsalis JC, Ma H, Ferrer S, Kirk K, Angulo-Barturen I, Kyle DE, DeRisi JL, Floyd DM, Guy RK 2014 PNAS View Researchers Basic research
Factor XIa-specific aptamers Sheffield WP, Donkor DA 2017 European Patent Office View Industry New or improved product or process
Using simulation to evaluate a blood supply network in the Canadian maritime provinces Blake J, Hardy M 2013 J Enterp Inf Manag View Researchers New or improved product or process
Severe autoimmune LMWH-induced thrombocytopenia presenting with aortic thromboses, adrenal hemorrhage and pulmonary embolism: response to high-dose intravenous immunoglobulin Nero J, Araneta P, Warkentin T, Moodley O 2018 Can J Gen Intern Med View Health care providers Clinical research
HIV Risk Factors Goldman M 2019 Screening Blood Donors with the Donor History Questionnaire View Blood operators Benchmarking and standard setting
The AABB Donor History Questionnaire O'Brien S, Carayiannis S 2019 Screening Blood Donors with the Donor History Questionnaire View Blood operators Benchmarking and standard setting
Age-Separated RBCs Show Changes in Oxygen Carrying Capacity and Rigidity During Hypothermic Storage Mykhailova O, Li W, Acker J 2019 Probl Cryobiol Cryomed View Researchers Basic research
Assessing the Vascular Deformability of Erythrocytes and Leukocytes: From Micropipettes to Microfluidics Scott M, Mathews K, Ma H 2019 Current and Future Aspects of Nanomedicine View Researchers Basic research
The association between influenza vaccination and socioeconomic status in high income countries varies by the measure used: a systematic review Lucyk K, Simmonds KA, Lorenzetti DL, Drews SJ, Svenson LW, Russell ML 2019 BMC Med Red Methodol View Researchers Clinical research
Canadian Blood Services should screen for behaviour, not sexual orientation Lachowsky NJ, Grace D 2019 Georgia Straight View Other Other
Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ?possible cohort effect following the 2009 influenza pandemic Skowronski DM, Leir S, De Serres G, Murti M, Dickinson JA, Winter A-L, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB 2019 Euro Surveill View Health care providers Clinical research
Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice Ya F, Xu XR, Tian Z, Gallant RC, Song F, Shi Y, Wu Y, Wan J, Zhao Y, Adili R, Ling W, Ni H, Yang Y 2020 Food Funct View Researchers Basic research
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin alpha II beta 3 Signaling and Thrombus Growth Ya F, Xu XR, Shi Y, Gallant RC, Song F, Zuo X, Zhao Y, Tian Z, Zhang C, Xu X, Ling W, Ni H, Yang Y 2019 Mol Nutr Food Res View Researchers Basic research
Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010–2015 Lam TT, Tang JW, Lai FY, Zaraket H, Dbaibo G, Bialasiewicz S, Tozer S, Heraud J-M, Drews SJ, Hachette T, Chan PKS, Koay ESC, Lee HK, Tee KK, Liu Y, Fraaij PLA, Jennings L, Waris M, Krajden M, Corriveau A, Jalal H, Nishimura H, Nymadawa P, Badarch D, Watanabe A, Kabanda A, Sloots T, Kok J, Dwyer DE, Koopmans M 2019 Journal of Infection View Health care providers Clinical research
Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients Chelle P, Yeung CHT, Bonanad S, Morales Munoz JC, Ozelo MC, Megias Vericat JE, Iorio A, Spears J, Mir R, Edginton A 2019 J Pharmacokinet Pharmacodyn View Health care providers Clinical research
Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization McEneny-King A, Chelle P, Foster G, Keepanasseril A, Iorio A, Edginton AN 2019 J Pharmacokinet Pharmacodyn View Researchers Clinical research
Correction to: Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients Chelle P, Yeung CHT, Bonanad S, Morales Munoz JC, Ozelo MC, Megias Vericat JE, Iorio A, Spears J, Mir R, Edginton A 2019 J Pharmacokinet Pharmacodyn View Health care providers Clinical research
Cryoprotection of platelets by grafted polymers Scott M, Nakane N, Maurer-Spurej E 2019 Cryopreservation - Current Advances and Evaluations View Researchers Basic research
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res Part B Appl Biomater View Researchers Basic research
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
An enzymatic pathway in the human gut microbiome that converts A to universal O type blood Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG 2019 Nat Microbiol View Researchers Basic research
COVID-19 Case Age Distribution: Correction for Differential Testing by Age Fisman DN, Greer A, Brankston G, Hillmer M, O'Brien SF, Drews S, Tuite AR 2021 Ann Intern Med View Researchers Clinical research
Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries Iorio A, Stonebraker JS, Chambost H, Makris M, Coffin D, Herr C, Germini F, for the Data Demographics Committee of the World Federation of Hemophilia 2019 Ann Intern Med View Researchers Clinical research
Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent Plasma Estcourt LJ, Cohn CS, Pagano MB, Iannizzi C, Kreuzberger N, Skoetz N, Allen ES, Bloch EM, Beaudoin G, Casadevall A, Devine DV, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Grossman BJ, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Tobian AAR 2022 Ann Intern Med View Health care providers Benchmarking and standard setting
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD 2022 BMC Public Health View Researchers MSM research
Stepping Stones or Second Class Donors?: a qualitative analysis of gay, bisexual, and queer men's perspectives on plasma donation policy in Canada Grace D, Gaspar M, Klassen B, Lessard D, Anand P, Brennan DJ, Lachowsky N, Adam BD, Cox J, Lambert G, Jollimore J, Hart TA 2021 BMC Public Health View Blood operators MSM research
Gay and bisexual men’s views on reforming blood donation policy in Canada: a qualitative study Grace D, Gaspar M, Lessard D, Klassen B, Brennan DJ, Adam BD, Jollimore J, Lachowsky NJ, Hart TA 2019 BMC Public Health View Researchers Other
Gay, Bisexual, and Queer Men Call for Equity and Evidence in Blood Donation Policy Grace D, Gaspar M, Lessard D, Klassen B, Brennan D, Adam B, Cox J, Moore D, Lambert G, Jollimore J, Lachowksy N, Hart T 2019 ENGAGE website View Other Other
High-dose intravenous immunoglobulin for the treatment and prevention of heparin-induced thrombocytopenia: a review Warkentin TE 2019 Expert Rev Hematol View Health care providers Clinical research
The Impact of Bacterial Biofilms in Transfusion Medicine Ramirez-Arcos S 2020 Racing for the Surface View Researchers Basic research
Influenza increases invasive meningococcal disease risk in temperate countries Salomon A, Berry I, Tuite AR, Drews S, Hatchette T, Jamieson F, Johnson C, Kwong J, Lina B, Lojo J, Mosnier A, Ng V, Vanhems P, Fisman DN 2020 Clin Microbiol Infect View Health care providers Clinical research
Intravenous immunoglobulin (IVIg) or IVIg-treated macrophages reduce DSS-induced colitis by inducing macrophage IL-10 production Kozicky LK, Menzies SC, Hotte N, Madsen KL, Sly LM 2019 Eur J Immunol View Researchers Basic research
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? Li J, Sullivan J, Ni H 2020 Cell Immunol View Researchers Basic research
Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry Pinto RN, Sebastian JA, Parsons MJ, Chang TC, Turner TR, Acker JP, Kolios MC 2019 Cytom Part A View Researchers New or improved product or process
Major reductions in unnecessary aspartate aminotransferase and blood urea nitrogen tests with a quality improvement initiative Strauss R, Cressman A, Cheung M, Weinerman A, Waldman S, Etchells E, Zahirieh A, Tartaro P, Tezmovitz J, Callum J 2019 BMJ Quality & Safety View Health care providers Clinical research
Model Human ? Thalassemic Erythrocytes: Effect of Unpaired Purified ?-Hemoglobin Chains on Normal Erythrocytes Scott M 2019 Beta Thalassemia View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2019 Industrial Engineering and Operations Management View Researchers New or improved product or process
Modulating the T Lymphocyte Immune Response via Secretome Produced miRNA: From Tolerance Induction to the Enhancement of the Anticancer Response Scott M, Wang D, Toyofuku W, Yang X 2019 Cells of the Immune System View Researchers Basic research
Efficacy and mechanism of intravenous immunoglobulin treatment for immune thrombocytopenia in adults Almizraq RJ, Branch DR 2020 Ann Blood View Health care providers Clinical research
Platelet physiology and immunology: pathogenesis and treatment of classical and non-classical fetal and neonatal alloimmune thrombocytopenia Chen ZY, Oswald BE, Sullivan JA, Dahmani FZ, Pasman Y, Liu Z, Chen P, Ni H 2019 Ann Blood View Researchers Basic research
Aging, chronic inflammation, and platelet hyperactivity Ma W, Karakas D, Chen ZY, Ni H 2020 Ann Blood View Researchers Basic research
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri Ramirez-Arcos S 2020 Ann Blood View Researchers Clinical research
Transfusion of a platelet pool contaminated with exotoxin-producing Staphylococcus aureus: a case report Chi SI, Kumaran D, Zeller M, Ramirez-Arcos S 2021 Ann Blood View Researchers Clinical research
Bacterial contamination of platelet components Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Ann Blood View Blood operators Benchmarking and standard setting