Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease Veljkovic V, Goeijenbier M, Glisic S, Veljkovic N, Perovic VR, Sencanski M, Branch DR, Paessler S 2015 F1000Res View Researchers Basic research
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa Sheffield WP, Eltringham-Smith LJ 2011 BMC Biotechnol View Researchers Basic research
A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss Sheffield WP, Eltringham-Smith LJ, Bhakta V 2018 BMC Biotechnol View Researchers Basic research
In-Gel Technology for PCR Genotyping and Pathogen Detection Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP 2010 Anal Chem View Researchers New or improved product or process
Inhibition of allogeneic cytotoxic T cell (CD8+) proliferation via polymer-induced Treg (CD4+) cells Kang N, Toyofuku WM, Yang X, Scott MD 2017 Acta Biomat View Researchers Basic research
Innate and adaptive immunity in immune thrombocytopenia Lazarus AH, Semple JW, Cines DB 2013 Semin Hematol View Researchers Clinical research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells Ratajczak MZ, Kim C, Ratajczak J, Janowska-Wieczorek A 2013 Complement Therapeutics View Researchers Basic research
Innate immunity as orchestrator of stem cell mobilization Ratajczak MZ, Kim CH, Wojakowski W, Janowska-Wieczorek A, Kucia M, Ratajczak J 2010 Leukemia View Researchers Basic research
Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex Ratajczak MZ, Lee H, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J 2010 Leukemia View Researchers Basic research
Intravenous Immunoglobulin (IVIg) Utilization in Immune Thrombocytopenia (ITP): A Multi-Center, Retrospective Review Hsia C, Liu Y, Eckert K, Monga N, Elia-Pacitti J, Heddle NM 2015 Drugs Real World Outcomes View Health care providers Clinical research
Introduction to the Special Issue: Teaching Healthcare Operations Research, Part 1 Blake J 2016 INFORMS Transactions on Education View Researchers Other
Introduction to the special issue: Teaching healthcare operations research, part 2 Blake J 2017 INFORMS Transactions on Education View Researchers New or improved product or process
IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist von Gunten S, Shoenfeld Y, Blank M, Branch DR, Vassilev T, Kasermann F, Bayry J, Kaveri S, Simon HU 2014 Nat Rev Immunol View Researchers Other
Lessons from vaccine-induced immune thrombotic thrombocytopenia Kelton JG, Arnold DM, Nazy I 2021 Nat Rev Immunol View Researchers Clinical research
IVIG-associated hemolysis: Its causes and potential resolution Branch D 2017 GBS/CIDP Foundation Spring/Summer 2017 Newsletter View Other Clinical research
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol View Researchers Basic research
How do I/we forecast tomorrows’ transfusion: Blood components Pereyra N, Devine DV 2023 Transfus Clin Biol View Health care providers New or improved product or process
Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data Caffrey N, Goldman M, Lewin A, Grégoire Y, Yi QL, O’Brien SF 2022 Transfus Clin Biol View Researchers MSM research
How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation Haw J, Holloway K, Goldman M 2023 Transfus Clin Biol View Researchers Ethical, legal & social implications research
L'étude ABLE : un essai clinique randomisé sur l'effet de la durée d'entreposage des concentrés érythrocytaires transfusés en réanimation Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Capellier G, Tiberghien P, Bardiaux L 2015 Transfus Clin Biol View Health care providers Clinical research
Label-free and noninvasive optical detection of the distribution of nanometer-size mitochondria in single cells Su X, Qiu Y, Marquez-Curtis L, Gupta M, Capjack CE, Rozmus W, Janowska-Wieczorek A, Tsui YY 2011 J Biomed Opt View Researchers New or improved product or process
Label-free assessment of red blood cell storage lesions by deep learning Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE 2018 bioRxiv View Researchers New or improved product or process
Legal Aspects of the Blood System in Canada Reis NM 2013 Public Health Law and Policy in Canada View Other Other
Legal Foundations of Public Health Law Reis NM 2013 Public Health Law and Policy in Canada View Other Other
Liposomes alter thermal phase behavior and composition of red blood cell membranes Stoll C, Stadnick H, Kollas O, Holovati JL, Glasmacher B, Acker JP, Wolkers WF 2011 Biochim Biophys Acta View Researchers Basic research
Proteolytic modulation of factor Xa-antithrombin complex enhances fibrinolysis in plasma Talbot K, Meixner SC, Pryzdial EL 2013 Biochim Biophys Acta View Researchers Basic research
Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles Bicalho B, Holovati JL, Acker JP 2013 Biochim Biophys Acta View Researchers Basic research
Liposomes composed of unsaturated lipids for membrane modification of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2011 Mol Membr Biol View Researchers Basic research
Long-term graft function following autologous hematopoietic cell transplantation and the impact of preemptive plerixafor in predicted poor mobilizers Visram A, Bredeson C, Allan D, Sabloff M, Huebsch L, Tay J, Kekre N, McDiarmid S, Mallick R, Tinmouth A, Martin L, Hamelin L, Maze D 2018 Blood Cancer J View Health care providers Clinical research
Low levels of interleukin-10 in patients with transfusion-related acute lung injury Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW 2017 Ann Transl Med View Researchers Clinical research
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS 2021 Vaccine View Researchers Clinical research
Low pertussis toxin antibody levels in two regional cohorts of Canadian pregnant women Bigham M, Konrad S, Van Buynder P, Van Buynder J, Isaac-Renton J, ElSherif M, Halperin SA 2014 Vaccine View Health care providers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia after COVID-19 vaccination: Description of a series of 39 cases in Brazil Mouta Nunes de Oliveira P, Mendes-de-Almeida DP, Bertollo Gomes Porto V, Crespo Cordeiro C, Vitiello Teixeira G, Saraiva Pedro R, Roberto Gomes Takey P, Kegele Lignani L, Reis Xavier J, Cardoso Doria da Gama V, Amorim Filho L, Emoingt Furtado B, Santa Maria A, Dahrug Barros T, Neves Waite Freitas L, Dos Santos Pereira T, Lima Abreu D, Bernardes Ramos M, Gabe C, Arnold D, William Smith J, Nazy I, Lourdes de Sousa Maia M 2022 Vaccine View Health care providers Clinical research
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
Acellular pertussis vaccine effectiveness and waning immunity in Alberta, Canada: 2010–2015, a Canadian Immunization Research Network (CIRN) study Bell CA, Russell ML, Drews SJ, Simmonds KA, Svenson LW, Schwartz KL, Kwong JC, Mahmud SM, Crowcroft NS 2019 Vaccine View Health care providers Clinical research
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
Management of immune-mediated thrombocytopenia Arnold DM, Nazi I, Smith JW, Warkentin TE 2016 Rossi's Principles of Transfusion Medicine View Health care providers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Bacterial contamination of blood components Bloch EM, Benjamin RJ, Ramirez-Arcos S 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Management of immune‐mediated thrombocytopenia Gabe C, Arnold D, Smith J, T W 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice Chen J, Reheman A, Gushiken FC, Nolasco L, Fu X, Moake JL, Ni H, Lopez JA 2011 J Clin Invest View Researchers Basic research
Maternal anti-platelet beta-3 integrins impair angiogenesis and cause intracranial hemorrhage Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai W-S, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen X-Y, Skogen B, Adamson SL, Freedman J, Ni H 2015 J Clin Invest View Researchers Basic research
The maternal immune response to fetal platelet GPIb? causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H 2011 J Clin Invest View Researchers Basic research
Plasma fibronectin supports hemostasis and regulates thrombosis Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H 2014 J Clin Invest View Researchers Basic research
Risk-assessment models for VTE and bleeding in hospitalized medical patients: an overview of systematic reviews Darzi AJ, Repp AB, Spencer FA, Morsi RZ, Charide R, Etxeandia-Ikobaltzeta I, Bauer KA, Burnett AE, Cushman M, Dentali F, Kahn SR, Rezende SM, Zakai NA, Agarwal A, Karam SG, Lotfi T, Wiercioch W, Waziry R, Iorio A, Akl EA, Schünemann HJ 2020 Blood Adv View Health care providers Clinical research
Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry Arnold DM, Nazy I, Clare R, Jaffer AM, Aubie B, Li N, Kelton JG 2017 Blood Adv View Health care providers Clinical research
Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion Ebraheem MS, Verhovsek M 2021 Blood Adv View Health care providers Clinical research
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA 2018 Blood Adv View Researchers Basic research