Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife View Researchers Clinical research
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Evaluation and Management of Proteinuria After Kidney Transplantation Tsampalieros A, Knoll GA 2015 Transplantation View Health care providers Clinical research
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS 2023 Transplantation View Researchers Basic research
Evidence of SARS-CoV-2 Infection in Cells, Tissues, and Organs and the Risk of Transmission Through Transplantation Gaussen A, Hornby L, Rockl G, O’Brien S, Delage G, Sapir-Pichhadze R, Drews SJ, Weiss MJ, Lewin A 2021 Transplantation View Health care providers Clinical research
Evidence of SARS-CoV-2 Infection in Cells, Tissues and Organs and the Risk of Transmission Through Transplantation Gaussen A, Hornby L, Rockl G, O'Brien S, Delage G, Sapir-Pichhadze R, Drews SJ, Weiss MJ, Lewin A 2021 Transplantation View Health care providers Clinical research
Thromboelastometry reveals similar hemostatic properties of purified fibrinogen and a mixture of purified cryoprecipitate protein components Qadri SM, Eltringham-Smith LJ, Bhakta V, Sheffield WP 2018 Clin Chem Lab Med View Researchers Basic research
Evaluation of the BacT/ALERT 3D system for the implementation of in-house quality control sterility testing at Canadian Blood Services Mastronardi C, Perkins H, Derksen P, denAdmirant M, Ramirez-Arcos S 2010 Clin Chem Lab Med View Blood operators New or improved product or process
The clinical significance of platelet microparticle-associated microRNAs Provost P 2017 Clin Chem Lab Med View Researchers Basic research
Exploring resource allocation and alternate clinic accessibility landscapes for improved blood donor turnout Paez A, Esita J, Newbold KB, Heddle NM, Blake JT 2013 Appl Geogr View Blood operators New or improved product or process
Combined preoperative plasma exchange and red blood cell exchange transfusion in a renal transplant patient with protein S deficiency and hemoglobin SC disease Cook O, Cervi A, Laureano M, Gangji AS, Verhovsek M 2021 Transfus Apher Sci View Researchers Clinical research
Extracellular vesicle characteristics in stored red blood cell concentrates are influenced by the method of detection Almizraq RJ, Seghatchian J, Holovati JL, Acker JP 2017 Transfus Apher Sci View Researchers Basic research
Residual Risk of HIV, HCV and HBV in Canada O'Brien SF, Yi Q-L, Fan W, Scalia V, Goldman M, Fearon MA 2017 Transfus Apher Sci View Health care providers Clinical research
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia— Principles and mechanisms Wabnitz H, Khan R, Lazarus AH 2020 Transfus Apher Sci View Researchers Clinical research
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Transfusion Camp: Successes and challenges in scaling and expanding a transfusion medicine education program Lin Y, Khandelwal A, Kapitany C, Chargé S 2023 Transfus Apher Sci View Health care providers Education research
The relationship of CD34+ dosage and platelet recovery following high dose chemotherapy and autologous CD34+ reinfusion in multiple myeloma Martin RMG, Ricci MJ, Foley R, Mian HS 2017 Transfus Apher Sci View Health care providers Clinical research
Assessment of extracellular vesicles using IFC for application in transfusion medicine Mykhailova O, Seghatchian J, Acker JP 2020 Transfus Apher Sci View Researchers Basic research
An online immunohematology educational resource for post-graduate hematology trainees: LearnSerology.ca Arsenault V, Yan MTS, Tait G, Lewin A, Pendergrast J 2023 Transfus Apher Sci View Health care providers Education research
Quality of frozen transfusable plasma prepared from whole blood donations in Canada: An update Sheffield WP, Bhakta V, Talbot K, Pryzdial ELG, Jenkins C 2013 Transfus Apher Sci View Blood operators Benchmarking and standard setting
Perioperative transfusion-related acute lung injury: The Canadian Blood Services experience Alam A, Huang M, Yi Q-L, Lin Y, Hannach B 2014 Transfus Apher Sci View Health care providers Other
Promoting access to COVID-19 convalescent plasma in low- and middle-income countries Bloch EM, Goel R, Montemayor C, Cohn C, Tobian AAR 2020 Transfus Apher Sci View Health care providers Clinical research
Platelet rich plasma in treatment of musculoskeletal pathologies Mehrabani D, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Update on newer approaches to prevent or treat COVID-19 infection: What we all need the most right now!! Seghatchian J, Acker JP, Putter JS 2020 Transfus Apher Sci View Researchers New or improved product or process
Acquired factor XIII deficiency: A review Yan MTS, Rydz N, Goodyear D, Sholzberg M 2018 Transfus Apher Sci View Researchers Other
Emerging use of machine learning and advanced technologies to assess red cell quality Sebastian JA, Kolios MC, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Blood coagulation dissected Pryzdial ELG, Lee FMH, Lin BH, Carter RLR, Tegegn TZ, Belletrutti MJ 2018 Transfus Apher Sci View Health care providers Other
A Canadian perspective on the use and preparation of cryopreserved red cell concentrates Turner TR, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017 Qadri SM, Donkor DA, Yan M, Ning S, Branch DR, Seghatchian J, Sheffield WP 2018 Transfus Apher Sci View Researchers Other
Optimizing the supply of whole blood-derived bioproducts through the combined implementation of cryopreservation and pathogen reduction technologies and practices: An overview Bohonek M, Kutac D, Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process
Opportunities for standardization of cold stored, low-titre group O WB products Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process
Spotlight on animal models of acute traumatic coagulopathy: An update Ask A, Eltringham-Smith L, Bhakta V, Donkor DA, Pryzdial ELG, Sheffield WP 2022 Transfus Apher Sci View Researchers Basic research
Extending the pre-processing holding time of whole blood beyond 48h reduces coagulation FVIII activity and immunoglobulin G content of recovered plasma Sheffield WP, Bhakta V, Jenkins C 2018 Transfus Apher Sci View Researchers New or improved product or process
Impact of organizational interventions on reducing inappropriate intravenous immunoglobulin (IVIG) usage: A systematic review and meta-analysis Diep C, Shih AW, Jamula E, Heddle NM, Parvizian M, Hillis CM 2018 Transfus Apher Sci View Health care providers Clinical research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science View Researchers Basic research
Fanconi anemia proteins and their interacting partners: a molecular puzzle Kaddar T, Carreau M 2012 Anemia View Researchers Basic research
Fast Facts: Opt-out Consent for Organ Donation Toews M 2017 Canadian National Transplant Research Program Fast Policy Facts View Other Other
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Platelets in Thrombosis and Hemostasis: Old Topic with New Mechanisms Wang Y, Andrews M, Yang Y, Lang S, Jin JW, Cameron-Vendrig A, Zhu G, Reheman A, Ni H 2012 Cardiovasc Hematol Disord Drug Targets View Health care providers Basic research
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research
Feasibility and transport of packed red blood cells into Special Forces operational conditions Boscarino C, Tien H, Acker J, Callum J, Hansen AL, Engels P, Glassberg E, Nathens A, Beckett A 2014 J Trauma Acute Care Surg View Other New or improved product or process
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME 2021 J Trauma Acute Care Surg View Researchers Benchmarking and standard setting
Febrile and allergic transfusion reactions Fung MK, Heddle NM 2013 Practical Transfusion Medicine, 4th edition View Health care providers Clinical research
Getting the Most Out of the Evidence for Transfusion Medicine Stanworth SJ, Brunskill SJ, Doree C, Sally Hopewell S, Arnold D 2013 Practical Transfusion Medicine, 4th edition View Health care providers Other
Scanning the future of transfusion medicine Devine D, Dzik WH, Szczepiorkowski ZM 2013 Practical Transfusion Medicine, 4th edition View Health care providers Other
Fetal and neonatal alloimmune thrombocytopenia Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H 2016 Semin Fetal Neonatal Med View Researchers Basic research
Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models Yougbare I, Zdravic D, Ni H 2018 J Pediatr Pediatr Med View Researchers Basic research
Fibronectin maintains the balance between hemostasis and thrombosis Wang Y, Ni H 2016 Cell Mol Life Sci View Researchers Basic research
Novel contact–kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke Zhang Z, Shen C, Fang M, Han Y, Long C, Liu W, Yang M, Liu M, Zhang D, Cao Q, Chen X, Fang Y, Lu Q, Hou Z, Li Y, Liu Z, Lei X, Ni H, Lai R 2022 Cell Mol Life Sci View Researchers Basic research
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF 2015 J Org Chem View Researchers Basic research