Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth View Researchers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group 2021 Vox Sang View Researchers Clinical research
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A 2020 medRxiv View Researchers Clinical research
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes Brydon M, Kephart G, Payne JI, Blake J 2020 J Med Imaging Radiat Sci View Researchers New or improved product or process
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM 2022 Transfusion View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP 2022 Blood Adv View Researchers Clinical research
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS 2023 Transplantation View Researchers Basic research
A Survey of Patient Experience in CML: American and Canadian Perspectives Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E 2023 Patient Prefer Adherence View Researchers Clinical research
Database-driven research and big data analytic approaches in transfusion medicine Ning S, Li N, Barty R, Arnold D, Heddle NM 2022 Transfusion View Researchers Clinical research
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP 2022 Vox Sang View Researchers Clinical research
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges Wolfe A 2022 Blood.ca website View Researchers Benchmarking and standard setting
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H 2017 Nat Commun View Researchers Basic research
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data Jordan A, Chen D, Yi QL, Kanias T, Gladwin MT, Acker JP 2016 Vox Sang View Researchers Basic research
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One View Researchers Basic research
C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury Kapur R, Kim M, Shanmugabhavananthan S, Liu J, Li Y, Semple JW 2015 Blood View Researchers Basic research
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units Pasha R, Elmoazzen H, Pineault N 2017 Transfusion View Researchers New or improved product or process
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry View Researchers Basic research
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF 2015 J Org Chem View Researchers Basic research
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost View Researchers Basic research
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH 2017 Blood View Researchers Basic research
In-Gel Technology for PCR Genotyping and Pathogen Detection Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP 2010 Anal Chem View Researchers New or improved product or process
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol View Researchers Basic research
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP Leontyev D, Katsman Y, Branch DR 2012 Blood View Researchers Basic research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express View Researchers Basic research
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? Chang TMS 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation Sutton TC, Scott MD 2010 Biomaterials View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Translational feasibility of soluble nanobiotherapeutics with enhanced red blood cell functions Chang TMS 2017 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion-transmissible infections Sharma RR, Lozano M, Fearon M, Bigham M, Djoudi R, Gallian P, Woimant G, Lee C, Leung JNS, Tsoi WC, Marwaha N, Sachdev S, Tadokoro K, Tani Y, Matsukura H, Gbuz So O, Shantseva N, Zhiburt E, Hindawi S, Chay J, Huang T, Teo D, Moleli N, Oyonarte S, Jayasekara SBA, Bokhorst A, van den Burg P, Hewitt P, Bianco C, Kessler D 2017 Vox Sang View Researchers Clinical research
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines Branch D 2018 Blood.ca website View Researchers Basic research
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water Devine DV 2018 JAMA Oncol View Researchers New or improved product or process
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM 2018 Transfusion View Researchers Clinical research
GPIb? is required for platelet-mediated hepatic thrombopoietin generation Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H 2018 Blood View Researchers Basic research
Prevalence of Babesia in Canadian blood donors: June–October 2018 Tonnetti L, O'Brien SF, Grégoire Y, Proctor MC, Drews SJ, Delage G, Fearon MA, Brès V, Linnen JM, Stramer SL 2019 Transfusion View Researchers Clinical research
Antiviral anticoagulation Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M 2020 Res Pract Thromb Haemost View Researchers Basic research
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2021 Haematologica View Researchers Basic research
Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol Fergusson DA, Chassé M, Tinmouth A, Acker JP, English S, Forster AJ, Hawken S, Shehata N, Thavorn K, Wilson K, Tuttle A, Perelman I, Cober N, Maddison H, Tokessy M 2021 BMJ Open View Researchers Clinical research
A simple protein-based surrogate neutralization assay for SARS-CoV-2 Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC 2020 JCI Insight View Researchers New or improved product or process
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood View Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion View Researchers New or improved product or process
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts Kaushal R, Jahan S, McGregor C, Pineault N 2022 Cytotherapy View Researchers New or improved product or process
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X 2023 Brit J Haem View Researchers Clinical research