Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Closing in on DEHP-free red blood cell concentrate containers Almizraq RJ, Acker J 2018 Transfusion View Researchers New or improved product or process
An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs U, Warkentin TE, Greinacher A 2019 J Thromb Haemost View Researchers New or improved product or process
Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review Siegal DM, Manning N, Jackson Chornenki NL, Hillis CM, Heddle NM 2018 J Intensive Care Med View Researchers New or improved product or process
Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice Ya F, Xu XR, Tian Z, Gallant RC, Song F, Shi Y, Wu Y, Wan J, Zhao Y, Adili R, Ling W, Ni H, Yang Y 2020 Food Funct View Researchers Basic research
Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2020 Haematologica View Researchers Basic research
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 Atreya C, Glynn S, Busch M, Kleinman S, Snyder E, Rutter S, AuBuchon J, Flegel W, Reeve D, Devine D, Cohn C, Custer B, Goodrich R, Benjamin RJ, Razatos A, Cancelas J, Wagner S, Maclean M, Gelderman M, Cap A, Ness P 2019 Transfusion View Researchers New or improved product or process
Assessment of extracellular vesicles using IFC for application in transfusion medicine Mykhailova O, Seghatchian J, Acker JP 2020 Transfus Apher Sci View Researchers Basic research
Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities Al-Riyami AZ, Schäfer R, van den Berg K, Bloch EM, Estcourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C 2020 Vox Sang View Researchers Clinical research
Effect of cryopreservation on a rare McLeod donor red blood cell concentrate Turner TR, Clarke G, Denomme GA, Skeate R, Acker JP 2021 Immunohematology View Researchers Basic research
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS 2021 Vaccine View Researchers Clinical research
GPIb? is the driving force of hepatic thrombopoietin generation Karakas D, Xu M, Ni H 2021 Res Pract Thromb Haem View Researchers Basic research
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T 2021 Blood View Researchers Basic research
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC 2021 Front Genet View Researchers Basic research
von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells Bowman M, Casey L, Selvam SN, Lima PDA, Rawley O, Hinds M, Tuttle A, Grabell J, Iorio A, Walker I, Lillicrap D, James P 2022 J Thromb Haemost View Researchers Basic research
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM 2023 Platelets View Researchers Clinical research
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR 2016 PLoS Negl Trop Dis View Researchers Basic research
Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets Yang Y, Andrews MC, Hu Y, Wang D, Qin Y, Zhu Y, Ni H, Ling W 2011 J Agric Food Chem View Researchers Basic research
Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? Gierczak RF, Bhakta V, Xie M, Sheffield WP 2015 J Biotechnol View Researchers Basic research
Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H 2016 Lab Chip View Researchers New or improved product or process
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JCM, Ni H, Ariens RAS, Wolberg AS 2015 Blood View Researchers Basic research
Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation Quinn KL, Henriques M, Tabuchi A, Han B, Yang H, Cheng W-E, Tole S, Yu H, Luo A, Charbonney E, Tullis E, Lazarus A, Robinson LA, Ni H, Peterson BR, Kuebler WM, Slutsky AS, Zhang H 2011 Arterioscler Thromb Vasc Biol View Researchers Basic research
Intracellular ice formation in confluent monolayers of human dental stem cells and membrane damage Zhurova M, Woods EJ, Acker JP 2010 Cryobiology View Researchers Basic research
Microfluidic analysis of red blood cell deformability Guo Q, Duffy SP, Matthews K, Santoso AT, Scott MD, Ma H 2014 J Biomech View Researchers Basic research
Mouse Models of Autoimmune Diseases: Immune Thrombocytopenia Neschadim A, Branch DR 2015 Current Pharmaceutical Design View Researchers Basic research
Osmotic tolerance limits of red blood cells from umbilical cord blood Zhurova M, Lusianti RE, Higgins AZ, Acker JP 2014 Cryobiology View Researchers Basic research
Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage Xu XR, Gallant RC, Ni H 2016 Thromb Res View Researchers Basic research
Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment Schubert P, Culibrk B, Karwal S, Goodrich RP, Devine DV 2016 Proteomics Clin Appl View Researchers Basic research
The effect of processing method on the in vitro characteristics of red blood cell products Hansen AL, Kurach JDR, Turner TR, Jenkins C, Busch MP, Norris PJ, Dugger J, Tomasulo PA, Devine DV, Acker JP 2015 Vox Sang View Researchers Basic research
The perioperative anticoagulant use for surgery evaluation (PAUSE) study for patients on a direct oral anticoagulant who need an elective surgery or procedure: design and rationale Douketis JD, Spyropoulos AC, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Le Gal G, Le Templier G, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S 2017 Thromb Haemost View Researchers Clinical research
Immunotherapy: the good, the bad, the ugly, and the really ugly Branch DR 2019 Transfusion View Researchers Clinical research
Contextual factors influencing donor recruitment and cord blood collection: perspectives of frontline staff of the Canadian Blood Services' Cord Blood Bank Haw J, Polzer J, Devine DV 2019 Transfusion View Researchers New or improved product or process
Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex Kipkeu BJ, Almizraq R, Branch DR, Acker JP, Holovati JL 2018 ISBT Sci Ser View Researchers Basic research
Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment Tseng EK, Jo D, Shih AW, De Wit K, Chan TM 2018 AEM Educ Train View Researchers Education research
Cryoprotection of platelets by grafted polymers Scott M, Nakane N, Maurer-Spurej E 2019 Cryopreservation - Current Advances and Evaluations View Researchers Basic research
Monitoring of prenatal patients using a combined antibody titre for Rh and non-Rh antibodies Farrell M, Clarke G, Barr G, Hannon J 2020 Transfus Med View Researchers Clinical research
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-?TP-L309C, a recombinant IgG1 Fc hexamer Lewis BJB, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher AW, Käsermann F, Branch DR 2019 BMC Immunol View Researchers Basic research
Concentré de recherche: L’apprentissage automatique pour mieux évaluer la qualité des globules rouges Acker JP 2020 Blood.ca website Researchers Basic research
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP 2021 Transfusion View Researchers New or improved product or process
Multicenter observational study evaluating the impact of platelet transport bags on product wastage Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J 2021 Transfusion View Researchers New or improved product or process
Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin Khan H, Gallant R, Jain S, Al-Omran M, De Mestral C, Greco E, Wheatcroft M, Alazonni A, Abdin R, Rand ML, Ni H, Qadura M 2020 Medicina View Researchers Clinical research
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P 2021 Res Pract Thromb Haemost View Researchers Clinical research
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A 2021 Transfusion View Researchers Clinical research
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I 2021 Nature View Researchers Clinical research
User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study Germini F, Borg Debono V, Page D, Zuk V, Kucher A, Cotoi C, Hobson N, Sevestre M, Skinner MW, Iorio A 2022 JMIR Hum Factors View Researchers Benchmarking and standard setting
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW 2021 Blood Coagul Fibrinolysis View Researchers Clinical research
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial Bartoszko J, Callum J, Karkouti K 2021 Can J Anaesth View Researchers Clinical research
A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates Chelle P, Iorio A, Edginton AN 2022 J Thromb Haemost View Researchers Basic research
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals Grunau B, Prusinkiewicz M, Asamoah-Boaheng M, Golding L, Lavoie PM, Petric M, Levett PN, Haig S, Barakauskas V, Karim ME, Jassem AN, Drews SJ, Sediqi S, Goldfarb DM 2022 Microbiol Spectr View Researchers Clinical research
Frequency and utility of bone marrow examination in relapsed/refractory immune thrombocytopenia Taparia K, Wall E, Arnold DM, Sun HL 2022 J Thromb Haemost View Researchers Clinical research