Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Cerebral venous sinus thrombosis associated with spontaneous heparin-induced thrombocytopenia syndrome after total knee arthroplasty Hwang SR, Wang Y, Weil EL, Padmanabhan A, Warkentin TE, Pruthi RK 2020 Platelets View Health care providers Clinical research
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM 2023 Platelets View Researchers Clinical research
Pathogen reduction technologies: The pros and cons for platelet transfusion Magron A, Laugier J, Provost P, Boilard E 2018 Platelets View Blood operators Basic research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
Megakaryocyte apoptosis in immune thrombocytopenia Vrbensky JR, Nazy I, Toltl LJ, Ross C, Ivetic N, Smith JW, Kelton JG, Arnold DM 2018 Platelets View Researchers Basic research
Development of antifouling and bactericidal coatings for platelet storage bags using dopamine chemistry Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE 2018 Adv Healthc Mater View Researchers New or improved product or process
Targeting activated platelets and fibrinolysis: hitting two birds with one stone Reheman A, Xu X, Reddy EC, Ni H 2014 Circ Res View Researchers Basic research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res View Researchers Basic research
Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Murphy MF, Tinmouth A 2014 Cochrane Database Syst Rev View Researchers Clinical research
Clotting factor concentrates for preventing bleeding and bleeding-related complications in previously treated individuals with haemophilia A or B Olasupo OO, Lowe MS, Krishan A, Collins P, Iorio A, Matino D 2021 Cochrane Database Syst Rev View Health care providers Clinical research
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC 2016 Cochrane Database Syst Rev View Health care providers Clinical research
Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support Estcourt LJ, Malouf R, Trivella M, Fergusson DA, Hopewell S, Murphy MF 2017 Cochrane Database Syst Rev View Health care providers Clinical research
Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells Purohit MK, Scovell I, Neschadim A, Katsman Y, Branch DR, Kotra LP 2013 Bioorg Med Chem Lett View Researchers Basic research
Do we know if we deplete or treat the donor's iron? Goldman M, Van den Burg P 2017 Transfusion Today View Health care providers Clinical research
COVID-19: Blood centres rise to the occasion and lead seroprevalence studies Lieshout-Krikke RW, O'Brien SF, Saeed S, Lewin A 2020 Transfusion Today Health care providers Clinical research
Canada's MSM Research Program - producing and mobilizing knowledge Chargé S, Haw J 2020 Transfusion Today Researchers MSM research
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D 2014 Syst Rev View Researchers Clinical research
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L 2014 Syst Rev View Researchers Clinical research
Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ 2016 Syst Rev View Researchers Basic research
Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis Hesketh CC, Knoll GA, Molnar AO, Tsampalieros A, Zimmerman DL 2014 Syst Rev View Researchers Clinical research
Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence Kayibanda JF, Hiremath S, Knoll GA, Fergusson D, Chow BJ, Shabana W, Akbari A 2014 Syst Rev View Researchers Clinical research
Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L 2015 Syst Rev View Researchers Clinical research
Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol Boutin A, Chasse M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Lacroix J, Fergusson DA, Desjardins P, Turgeon AF 2014 Syst Rev View Researchers Other
In silico analysis suggests interaction between Ebola virus and the extracellular matrix Veljkovic V, Glisic S, Muller CP, Scotch M, Branch DR, Perovic VR, Sencanski M, Veljkovic N, Colombatti A 2015 Front Microbiol View Researchers Basic research
Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms Kumaran D, Taha M, Yi Q, Ramirez-Arcos S, Diallo JS, Carli A, Abdelbary H 2018 Front Microbiol View Researchers Basic research
Drugs in ITP: Mechanisms of Action Crow AR, Lazarus AH 2013 Immune Thrombocytopenia (ITP) View Researchers Other
Eadie-Hofstee analysis of red blood cell deformability Stadnick H, Onell R, Acker JP, Holovati JL 2011 Clin Hemorheol Microcirc View Researchers Basic research
Ebola virus VP35 blocks stress granule assembly Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ 2017 Virology View Researchers Basic research
The immune-stimulation capacity of liposome-treated red blood cells da Silveira Cavalcante L, Branch DR, Duong TT, Yeung RSM, Acker JP, Holovati JL 2017 J Liposome Res View Researchers Basic research
Effect of liposome-treated red blood cells in an anemic rat model da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker JP, Holovati JL 2016 J Liposome Res View Researchers Basic research
Generic immunosuppression in solid organ transplantation: systematic review and meta-analysis Molnar AO, Fergusson D, Tsampalieros AK, Bennett A, Fergusson N, Ramsay T, Knoll GA 2015 BMJ View Health care providers Clinical research
Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data Knoll GA, Kokolo MB, Mallick R, Beck A, Buenaventura CD, Ducharme R, Barsoum R, Bernasconi C, Blydt-Hansen TD, Ekberg H, Felipe CR, Firth J, Gallon L, Gelens M, Glotz D, Gossmann J, Guba M, Morsy AA, Salgo R, Scheuermann EH, Tedesco-Silva H, Vitko S, Watson C, Fergusson DA 2014 BMJ View Health care providers Clinical research
Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis Siemieniuk RA, Bartoszko JJ, Díaz Martinez JP, Kum E, Qasim A, Zeraatkar D, Izcovich A, Mangala S, Ge L, Han MA, Agoritsas T, Arnold D, Ávila C, Chu DK, Couban R, Cusano E, Darzi AJ, Devji T, Foroutan F, Ghadimi M, Khamis A, Lamontagne F, Loeb M, Miroshnychenko A, Motaghi S, Murthy S, Mustafa RA, Rada G, Rochwerg B, Switzer C, Vandvik PO, Vernooij RW, Wang Y, Yao L, Guyatt GH, Brignardello-Petersen R 2021 BMJ View Researchers Clinical research
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature Dyba J, Tinmouth A, Bredeson C, Matthews J, Allan DS 2016 Transfus Med View Researchers Clinical research
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Endothelial-Specific Deletion of Autophagy Related 7 (ATG7) Attenuates Arterial Thrombosis in Mice Yau JW, Singh KK, Hou Y, Lei X, Ramadan A, Quan A, Teoh H, Kuebler WM, Al-Omran M, Yanagawa B, Ni H, Verma S 2017 J Thorac Cardiovasc Surg View Researchers Basic research
Engineering biomaterials surfaces to modulate the host response Yu K, Mei Y, Hadjesfandiari N, Kizhakkedathu JN 2014 Colloids Surf B Biointerfaces View Researchers Basic research
Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions Rossi NAA, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN 2010 J Am Chem Soc View Researchers Basic research
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution Kwan DH, Constantinescu I, Chapanian R, Higgins MA, Kotzler MP, Samain E, Boraston AB, Kizhakkedathu JN, Withers SG 2015 J Am Chem Soc View Researchers New or improved product or process
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry View Researchers Basic research
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers Wang A, Kluger R 2014 Biochemistry View Researchers Basic research
Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis Marquez-Curtis LA, Janowska-Wieczorek A 2013 BioMed Res Int View Researchers Basic research
Epigenetic regulation of endothelial-cell-mediated vascular repair Fraineau S, Palii CG, Allan DS, Brand M 2015 FEBS J View Researchers Other
Erroneous HbA1c results in a patient with elevated HbC and HbF Adekanmbi J, Higgins T, Rodriguez-Capote K, Thomas D, Winterstein J, Dixon T, Gifford JL, Krause R, Venner AA, Clarke G, Estey MP 2016 Clinica Chimica Acta View Health care providers Clinical research
Impact of technical and assay variation on reporting of hemolysis in stored red blood cell products Almizraq RJ, Yi QL, Acker JP 2017 Clinica Chimica Acta View Blood operators New or improved product or process
Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes Qadri SM, Bissinger R, Solh Z, Oldenborg PA 2017 Blood Rev View Researchers Basic research
The recipe for TACO: A narrative review on the pathophysiology and potential mitigation strategies of transfusion-associated circulatory overload Bulle EB, Klanderman RB, Pendergrast J, Cserti-Gazdewich C, Callum J, Vlaar APJ 2022 Blood Rev View Health care providers Clinical research
Evaluating Health Care Policy Decisions: Canadian Blood Services in Atlantic Canada Blake JT, Rogerson M, Harris D 2013 Operations Research and Health Care Policy View Other New or improved product or process