Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV 2021 Transfusion View Researchers Basic research
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time Stonebraker JS, O'Mahony B, Noone D, Iorio A 2021 Haemophilia View Researchers Benchmarking and standard setting
Evaluation of the sexual health in people living with hemophilia Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A 2021 Haemophilia View Researchers Clinical research
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD 2022 BMC Public Health View Researchers MSM research
A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic Grunau B, O’Brien SF, Kirkham TL, Helmer J, Demers PA, Asamoah-Boaheng M, Drews SJ, Karim ME, Srigley JA, Sediqi S, O’Neill D, Drennan IR, Goldfarb DM 2022 Ann Emerg Med View Researchers Clinical research
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS 2023 Cytotherapy View Researchers Clinical research
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply Mahamad S, Li N, Arnold DM 2023 J Thromb Haemost View Researchers Clinical research
Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor Gierczak RF, Pepler L, Bhagirath V, Liaw PC, Sheffield WP 2014 Thromb Res View Researchers Basic research
Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae Ruddock PS, Charland M, Ramirez S, Lopez A, Neil Towers GH, Arnason JT, Liao M, Dillon JA 2011 Sex Transm Dis View Researchers Basic research
Cadherin 6 has a functional role in platelet aggregation and thrombus formation Dunne E, Spring CM, Reheman A, Jin W, Berndt MC, Newman DK, Newman PJ, Ni H, Kenny D 2012 Arterioscler Thromb Vasc Biol View Researchers Basic research
Concentré de recherche: L'immunocamouflage au service des greffés et des transplantés Scott M 2017 Blood.ca website View Researchers Basic research
Designing ice recrystallization inhibitors: from antifreeze (glyco)proteins to small molecules Balcerzak AK, Capicciotti CJ, Briard JG, Ben RN 2014 RSC Adv View Researchers Basic research
Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms Kumaran D, Taha M, Yi Q, Ramirez-Arcos S, Diallo JS, Carli A, Abdelbary H 2018 Front Microbiol View Researchers Basic research
Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression Hubert A, Subra C, Jenabian MA, Tremblay Labrecque PF, Tremblay C, Laffont B, Provost P, Routy JP, Gilbert C 2015 J Acquir Immune Defic Syndr View Researchers Basic research
Fetal and neonatal alloimmune thrombocytopenia Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H 2016 Semin Fetal Neonatal Med View Researchers Basic research
Minimal dataset for post-registration surveillance of new drugs in hemophilia: communication from the SSC of the ISTH Peyvandi F, Makris M, Collins P, Lillicrap D, Pipe SW, Iorio A, Rosendaal FR 2017 J Thromb Haemost View Researchers Clinical research
Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP 2017 Transfusion View Researchers Basic research
Quality control of apheresis platelets: a multicentre study to evaluate factors that can influence pH measurement Germain M, Grégoire Y, Vassallo RR, Acker JP, Cardigan R, de Korte D, Irving DO, Bégué S, on behalf of the BEST Collaborative 2017 Vox Sang View Researchers New or improved product or process
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
Synergistic effects of liposomes, trehalose, and hydroxyethyl starch for cryopreservation of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2012 Biotechnol Prog View Researchers New or improved product or process
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Closing in on DEHP-free red blood cell concentrate containers Almizraq RJ, Acker J 2018 Transfusion View Researchers New or improved product or process
Risk-based decision making in transfusion medicine Leach Bennett J, Devine DV 2018 Vox Sang View Researchers New or improved product or process
Human T-cell lymphotropic virus: A simulation model to estimate residual risk with universal leucoreduction and testing strategies in Canada O'Brien SF, Yi Q-L, Goldman M, Grégoire Y, Delage G 2018 Vox Sang View Researchers New or improved product or process
Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review Rash JA, Buckley N, Busse JW, Campbell TS, Corace K, Cooper L, Flusk D, Iorio A, Lavoie KL, Poulin PA, Skidmore B 2018 Systematic Reviews View Researchers Clinical research
Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets Ni R, Neves MAD, Wu C, Cerroni SE, Flick MJ, Ni H, Weitz JI, Gross PL, Kim PY 2020 Thromb Haemost View Researchers Basic research
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H 2021 Transfusion View Researchers New or improved product or process
Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP Khan R, Menard M, Jen C-C, Chen X, Norris PAA, Lazarus AH 2020 Blood View Researchers Basic research
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC 2020 Sci Immunol View Researchers Clinical research
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M 2021 Transfusion View Researchers Basic research
T cell-mediated autoimmunity in immune thrombocytopenia Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM 2022 Eur J Haematol View Researchers Clinical research
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME 2021 J Trauma Acute Care Surg View Researchers Benchmarking and standard setting
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals Bulmer T, Volders D, Blake J, Kamal N 2021 Front Neurol View Researchers New or improved product or process
Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial Bartoszko J, Martinez-Perez S, Callum J, Karkouti K, Farouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke H-P, Carroll J, Grewal D, Brar S, Brussières J, Grocott H, Harle C, Pavenski K, Rochon A, Saha T, Shepherd L, Syed S, Tran D, Wong D, Zeller M 2022 Br J Anaesth View Researchers Clinical research
Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel Dibernardo A, Toledo NP, Robinson A, Osiowy C, Giles E, Day J, Lindsay LR, Drebot MA, Booth TF, Pidduck T, Baily A, Charlton CL, Tipples G, Kanji JN, Brochu G, Lang A, Therrien C, Bélanger-Collard M, Beaulac S-N, Gilfix BM, Boivin G, Hamelin M-È, Carbonneau J, Lévesque S, Martin P, Finzi A, Gendron-Lepage G, Goyette G, Benlarbi M, Gasser R, Fortin C, Martel-Lafferrière V, Lavoie M, Guérin R, Haraoui L-P, Renaud C, Jenkins C, O'Brien SF, Drews SJ, Conrod V, Tran V, Awrey B, Scheuermann R, DuPuis A, Payne A, Warszycki C, Girardin R, Lee W, Zahariadis G, Jiao L, Needle R, Cordenbach J, Zaharatos J, Taylor K, Teltscher M, Miller M, Elsherif M, Robertson P, Robinson JL 2022 J Assoc Med Microbiol Infect Dis Can View Researchers Benchmarking and standard setting
The bending rigidity of the red blood cell cytoplasmic membrane Himbert S, D’Alessandro A, Qadri SM, Majcher MJ, Hoare T, Sheffield WP, Nagao M, Nagle JF, Rheinstädter MC 2022 PLoS One View Researchers Basic research
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M 2023 PLoS One View Researchers Clinical research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
Assessment of antibody-based drugs effects on murine bone marrow and peritoneal macrophage activation Kozicky L, Sly LM 2017 J Vis Exp View Researchers Basic research
CD44 antibody-mediated amelioration of murine immune thrombocytopenia (ITP): mouse background determines the effect of FcgammaRIIb genetic disruption Crow AR, Amash A, Lazarus AH 2014 Transfusion View Researchers Basic research
Cryopreservation of adult unrelated donor products in hematopoietic cell transplantation: the OneMatch experience and systematic review of the literature Aziz J, Morris G, Rizk M, Shorr R, Mercer D, Young K, Allan D 2017 Transfusion View Researchers Clinical research
Development of a proof of principle for universal neutralization of antibiotics in cord blood by-products used for sterility testing Kou Y, Halpenny M, Elmoazzen H, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Enhancement of biological reactions on cell surfaces via macromolecular crowding Chapanian R, Kwan DH, Constantinescu I, Shaikh FA, Rossi NA, Withers SG, Kizhakkedathu JN 2014 Nat Commun View Researchers Basic research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy Wang D, Shanina I, Toyofuku WM, Horwitz MS, Scott MD 2015 PLoS One View Researchers Basic research
Label-free and noninvasive optical detection of the distribution of nanometer-size mitochondria in single cells Su X, Qiu Y, Marquez-Curtis L, Gupta M, Capjack CE, Rozmus W, Janowska-Wieczorek A, Tsui YY 2011 J Biomed Opt View Researchers New or improved product or process
Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL HIT-Ab(PF4-H)] for the diagnosis of immune heparin-induced thrombocytopenia Warkentin TE, Sheppard J-AI, Linkins L-A, Arnold DM, Nazy I 2017 Thromb Res View Researchers Clinical research
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
Prevention of Thrombogenesis from Whole Human Blood on Plastic Polymer by Ultrathin Monoethylene Glycol Silane Adlayer Fedorov K, Blaszykowski C, Sheikh S, Reheman A, Romaschin A, Ni H, Thompson M 2014 Langmuir View Researchers Basic research