Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort descending | Link to Article | Intended Audience | Purpose |
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T cell-mediated autoimmunity in immune thrombocytopenia | Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM | 2022 | Eur J Haematol | View T cell-mediated autoimmunity in immune thrombocytopenia | Researchers | Clinical research |
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia | Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG | 2015 | Eur J Haematol | View Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia | Researchers | Clinical research |
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia | Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM | 2013 | Eur J Haematol | View A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia | Health care providers | Clinical research |
Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study | Lane SJ, Sholapur NS, Yeung CH, Iorio A, Heddle NM, Sholzberg M, Pai M | 2016 | Haemophilia | View Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study | Health care providers | Other |
A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia | Lucier KJ, Movilla RV, Parvizian MK, Siddiqui R, Gabriele EH, Bourque M, MacIsaac J, Moorehead PC, Chan AK, Heddle NM, Lane SJ | 2018 | Haemophilia | View A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia | Health care providers | Clinical research |
Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement | Iorio A, Iserman E, Blanchette V, Dolan G, Escuriola Ettingshausen C, Hermans C, Negrier C, Oldenburg J, Reininger A, Rodriguez-Merchan C, Spannagl M, Valentino LA, Young G, Steinitz-Trost KN, Gringeri A | 2017 | Haemophilia | View Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement | Health care providers | Clinical research |
Patterns of joint damage in severe haemophilia A treated with prophylaxis | Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM | 2021 | Haemophilia | View Patterns of joint damage in severe haemophilia A treated with prophylaxis | Health care providers | Clinical research |
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A | 2015 | Haemophilia | View A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Health care providers | Clinical research |
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I | 2014 | Haemophilia | View First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Health care providers | Clinical research |
Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers | Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A | 2022 | Haemophilia | View Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers | Researchers | Ethical, legal and social implications research |
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM | 2014 | Haemophilia | View What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Health care providers | Other |
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study | Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ | 2017 | Haemophilia | View Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study | Researchers | Clinical research |
Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature | Iorio A, Königs C, Reding MT, Rotellini D, Skinner MW, Mancuso ME, Berntorp E | 2023 | Haemophilia | View Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature | Health care providers | Clinical research |
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers | Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM | 2013 | Haemophilia | View What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers | Health care providers | Other |
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes | Pierce GF, Iorio A | 2018 | Haemophilia | View Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes | Health care providers | New or improved product or process |
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes | Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S | 2021 | Haemophilia | View Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes | Researchers | Clinical research |
Switching to extended half-life products in Canada - preliminary data | Keepanasseril A, Stoffman J, Bouskill V, Carcao M, Iorio A, Jackson S | 2017 | Haemophilia | View Switching to extended half-life products in Canada - preliminary data | Health care providers | Clinical research |
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains | Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A | 2019 | Haemophilia | View Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains | Researchers | Clinical research |
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach | Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE | 2015 | Haemophilia | View Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach | Health care providers | Clinical research |
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Stonebraker JS, O'Mahony B, Noone D, Iorio A | 2021 | Haemophilia | View Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Researchers | Benchmarking and standard setting |
Evaluation of the sexual health in people living with hemophilia | Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A | 2021 | Haemophilia | View Evaluation of the sexual health in people living with hemophilia | Researchers | Clinical research |
The importance of haemophilia treatment centre administrators in patient care | Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK | 2012 | Haemophilia | View The importance of haemophilia treatment centre administrators in patient care | Health care providers | Other |
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM | 2020 | Haemophilia | View Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Researchers | Clinical research |
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A | 2018 | Haemophilia | View Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Health care providers | Clinical research |
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Iorio A, Edginton AN | 2017 | Haemophilia | View Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Researchers | Clinical research |
Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation | Lawson W, Uy M, Strike K, Iorio A, Stein N, Koziol L, Chan A | 2017 | Haemophilia | View Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation | Health care providers | Clinical research |
Emicizumab state-of-the-art update | Mahlangu J, Iorio A, Kenet G | 2022 | Haemophilia | View Emicizumab state-of-the-art update | Health care providers | Clinical research |
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics | Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R | 2022 | Haemophilia | View Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics | Researchers | Clinical research |
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project | Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S | 2018 | Haemophilia | View Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project | Health care providers | Clinical research |
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A | Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A | 2021 | Haemophilia | View Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A | Researchers | Clinical research |
Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population | Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdre L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM | 2018 | Haemophilia | View Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population | Health care providers | Clinical research |
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada | Fearon MA, Scalia V, Huang M, Dines I, Ndao M | 2013 | Can J Infect Dis Med Microbiol | View A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada | Health care providers | Clinical research |
Bacterial growth in red blood cell units exposed to uncontrolled temperatures: challenging the 30-minute rule | Ramirez-Arcos S, Perkins H, Kou Y, Mastronardi C, Kumaran D, Taha M, Yi QL, McLaughlin N, Kahwash E, Lin Y, Acker J | 2013 | Vox Sang | View Bacterial growth in red blood cell units exposed to uncontrolled temperatures: challenging the 30-minute rule | Regulators | New or improved product or process |
International Forum on the Management of Major Haemorrhage: Summary | Green L, Stanworth S, McQuilten Z, Lin V, Tucker H, Jackson B, Badawi M, Hindawi S, Chaurasia R, Patidar G, Pandey HC, Fasola F, Miyata S, Matsumoto M, Matsushita T, Rahimi-Levene N, Peer V, Pavenski K, Callum J, Thompson T, Murphy M, Staves J, Maegele M, Abeyakoon C, Rushford K, Wood E, Nuñez MA, Mellado S, Saa E, Triyono T, Pratomo B, Apelseth TO, Dunbar N | 2022 | Vox Sang | View International Forum on the Management of Major Haemorrhage: Summary | Health care providers | Benchmarking and standard setting |
Experiences with semi-routine production of riboflavin and UV-B pathogen-inactivated platelet concentrates in three blood centres | van der Meer PF, Couture C, Hervig T, Kruit G, Devine DV, de Korte D, Kerkhoffs JL | 2017 | Vox Sang | View Experiences with semi-routine production of riboflavin and UV-B pathogen-inactivated platelet concentrates in three blood centres | Blood operators | New or improved product or process |
Hepatitis E | Petrik J, Lozano M, Seed CR, Faddy HM, Keller AJ, Prado Scuracchio PS, Wendel S, Andonov A, Fearon M, Delage G, Zhang J, Shih JWK, Gallian P, Djoudi R, Tiberghien P, Izopet J, Dreier J, Vollmer T, Knabbe C, Aggarwal R, Goel A, Ciccaglione AR, Matsubayashi K, Satake M, Tadokoro K, Jeong S-H, Zaaijer HL, Zhiburt E, Chay J, Teo D, Chua SS, Piron M, Sauleda S, EchevarrÃa J-M, Dalton H, Stramer SL | 2016 | Vox Sang | View Hepatitis E | Blood operators | Other |
Sex-mismatched red blood cell transfusions and mortality: A systematic review and meta-analysis | Zeller MP, Rochwerg B, Jamula E, Li N, Hillis C, Acker JP, Runciman RJR, Lane SJ, Ahmed N, Arnold DM, Heddle NM | 2019 | Vox Sang | View Sex-mismatched red blood cell transfusions and mortality: A systematic review and meta-analysis | Researchers | Clinical research |
International Forum on Gender Identification and Blood Collection: Summary | Pandey S, Gorlin JB, Townsend M, Van Buren N, Leung JNS, Lee CK, van den Hurk K, Casamitjana N, Valles R, Alonso E, Miller YM, Richard P, Woimant G, Tiberghien P, Zhiburt E, Butler-Foster T, Goldman M, Nissen-Meyer LSH, Espinosa A, Kamel H, Bravo M, Filho LA, Pecego M, Germain M, Rabusseau I, Shinar E, Raz H, Choudhury N, Bhatnagar N, Hurt K, Lopez M, Reik RA, Nie Y, Hung Y, Pheello L, Dunbar N | 2022 | Vox Sang | View International Forum on Gender Identification and Blood Collection: Summary | Blood operators | Benchmarking and standard setting |
Determinants of the intention to participate in a programme of plasma donation for fractionation among men who have sex with men | Veillette-Bourbeau L, Otis J, Lewin A, Godin G, Germain M, Daunais-Laurin G, Lalonde F, Caruso J, Myhal G, Pronovost F | 2021 | Vox Sang | View Determinants of the intention to participate in a programme of plasma donation for fractionation among men who have sex with men | Researchers | MSM research |
Reducing the age of transfused red blood cells in hospitals: ordering and allocation policies | Sarhangian V, Abouee-Mehrizi H, Baron O, Berman O, Heddle NM, Barty R | 2016 | Vox Sang | View Reducing the age of transfused red blood cells in hospitals: ordering and allocation policies | Health care providers | Benchmarking and standard setting |
Risk-based decision-making for blood safety: preliminary report of a consensus conference | Stein J, Besley J, Brook C, Hamill M, Klein E, Krewski D, Murphy G, Richardson M, Sirna J, Skinner M, Steiner R, van Aken P, Devine D | 2011 | Vox Sang | View Risk-based decision-making for blood safety: preliminary report of a consensus conference | Blood operators | Other |
Targeted recruitment of male donors for allogeneic haematopoietic cell transplantation: A review of the evidence | Fingrut W, Rikhraj K, Allan D | 2018 | Vox Sang | View Targeted recruitment of male donors for allogeneic haematopoietic cell transplantation: A review of the evidence | Blood operators | Clinical research |
The impact of red blood cell manufacturing variables on bacterial growth dynamics: a pilot study | Ramirez-Arcos S, Kou Y, Cayer M-P, De Grandmont M-J, Girard M, Cloutier M | 2019 | Vox Sang | View The impact of red blood cell manufacturing variables on bacterial growth dynamics: a pilot study | Researchers | Basic research |
Overcoming the deceptively low viability of CD45+ cells in thawed cord blood unit segments | Pasha R, Halpenny M, Pineault N | 2019 | Vox Sang | View Overcoming the deceptively low viability of CD45+ cells in thawed cord blood unit segments | Researchers | New or improved product or process |
Establishment of Transfusion-Relevant Bacteria Reference Strains for Red Blood Cells | Prax M, Spindler-Raffel E, McDonald CP, Bearne J, Satake M, Kozakai M, Rojo J, Hanschmann K-MO, Lambrecht B, Grundmann U, O’Flaherty N, Klimek A, Bekeredjian-Ding I, Gathof BS, Störmer M, Süßner S, Renke C, Lee C-k, Knabbe C, Vollmer T, Keil SD, Shipps ME, Wagner SJ, Jentsch U, Mpumlwana X, Cloutier M, Bringmann P, Lu T, Ramirez-Arcos S, Kou Y, Krut O, ISBT Transfusion-Transmitted Infectious Diseases Working Party SoB | 2020 | Vox Sang | View Establishment of Transfusion-Relevant Bacteria Reference Strains for Red Blood Cells | Researchers | New or improved product or process |
Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study | Ramirez-Arcos S, Kou Y, Kumaran D, Culibrk B, Stewart T, Schubert P, McTaggart K | 2022 | Vox Sang | View Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study | Researchers | New or improved product or process |
A clinical governance framework for blood services | Williamson LM, Benjamin RJ, Devine DV, Katz LM, Pink J, for the Alliance of Blood Operators Medical Directors Group | 2015 | Vox Sang | View A clinical governance framework for blood services | Blood operators | Other |
Counting platelets at transfusion threshold levels: impact on the decision to transfuse. A BEST Collaborative - UK NEQAS(H) International Exercise | Lozano M, Mahon A, van der Meer PF, Stanworth S, Cid J, Devine D, Fung MK, de la Salle B, Heddle NM, on behalf of Biomedical Excellence for Safer Transfusion Collaborative | 2014 | Vox Sang | View Counting platelets at transfusion threshold levels: impact on the decision to transfuse. A BEST Collaborative - UK NEQAS(H) International Exercise | Health care providers | Benchmarking and standard setting |
50 years of Vox Sanguinis International Forums | Lozano M, Dunbar NM, Devine DV | 2020 | Vox Sang | View 50 years of Vox Sanguinis International Forums | Researchers | Benchmarking and standard setting |
Comparison of bacterial attachment to platelet bags with and without preconditioning with plasma | Loza-Correa M, Kalab M, Yi QL, Eltringham?Smith L, Sheffield W, Ramirez-Arcos S | 2017 | Vox Sang | View Comparison of bacterial attachment to platelet bags with and without preconditioning with plasma | Researchers | Basic research |