Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Monitoring of prenatal patients using a combined antibody titre for Rh and non-Rh antibodies | Farrell M, Clarke G, Barr G, Hannon J | 2020 | Transfus Med | View Monitoring of prenatal patients using a combined antibody titre for Rh and non-Rh antibodies | Researchers | Clinical research |
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-?TP-L309C, a recombinant IgG1 Fc hexamer | Lewis BJB, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher AW, Käsermann F, Branch DR | 2019 | BMC Immunol | View Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-?TP-L309C, a recombinant IgG1 Fc hexamer | Researchers | Basic research |
Concentré de recherche: L’apprentissage automatique pour mieux évaluer la qualité des globules rouges | Acker JP | 2020 | Blood.ca website | Researchers | Basic research | |
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation | Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP | 2021 | Transfusion | View Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation | Researchers | New or improved product or process |
Multicenter observational study evaluating the impact of platelet transport bags on product wastage | Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J | 2021 | Transfusion | View Multicenter observational study evaluating the impact of platelet transport bags on product wastage | Researchers | New or improved product or process |
Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin | Khan H, Gallant R, Jain S, Al-Omran M, De Mestral C, Greco E, Wheatcroft M, Alazonni A, Abdin R, Rand ML, Ni H, Qadura M | 2020 | Medicina | View Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin | Researchers | Clinical research |
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study | Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P | 2021 | Res Pract Thromb Haemost | View Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study | Researchers | Clinical research |
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma | Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A | 2021 | Transfusion | View Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma | Researchers | Clinical research |
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I | 2021 | Nature | View Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Researchers | Clinical research |
User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study | Germini F, Borg Debono V, Page D, Zuk V, Kucher A, Cotoi C, Hobson N, Sevestre M, Skinner MW, Iorio A | 2022 | JMIR Hum Factors | View User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study | Researchers | Benchmarking and standard setting |
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography | Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW | 2021 | Blood Coagul Fibrinolysis | View Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography | Researchers | Clinical research |
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial | Bartoszko J, Callum J, Karkouti K | 2021 | Can J Anaesth | View The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial | Researchers | Clinical research |
A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates | Chelle P, Iorio A, Edginton AN | 2022 | J Thromb Haemost | View A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates | Researchers | Basic research |
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals | Grunau B, Prusinkiewicz M, Asamoah-Boaheng M, Golding L, Lavoie PM, Petric M, Levett PN, Haig S, Barakauskas V, Karim ME, Jassem AN, Drews SJ, Sediqi S, Goldfarb DM | 2022 | Microbiol Spectr | View Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals | Researchers | Clinical research |
A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V | Talbot K, Song J, Hewitt J, Serrano K, Ho M, Carter CJ, MacGillivray RTA, Pryzdial ELG | 2010 | Br J Haematol | View A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V | Researchers | Basic research |
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M | 2016 | Sci Rep | View CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Researchers | Basic research |
Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation | Vanden Hoek AL, Talbot K, Carter IS, Vickars L, Carter CJ, Jackson SC, Macgillivray RT, Pryzdial EL | 2012 | J Thromb Haemost | View Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation | Researchers | Basic research |
c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines | McCarthy SDS, Jung D, Sakac D, Branch DR | 2014 | J Acquir Immune Defic Syndr | View c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines | Researchers | Basic research |
Drugs in ITP: Mechanisms of Action | Crow AR, Lazarus AH | 2013 | Immune Thrombocytopenia (ITP) | View Drugs in ITP: Mechanisms of Action | Researchers | Other |
Enhancing blood donor skin disinfection using natural oils | Alabdullatif M, Boujezza I, Mekni M, Taha M, Kumaran D, Yi QL, Landoulsi A, Ramirez-Arcos S | 2017 | Transfusion | View Enhancing blood donor skin disinfection using natural oils | Researchers | New or improved product or process |
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Iorio A, Edginton AN | 2017 | Haemophilia | View Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Researchers | Clinical research |
High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators | Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ | 2017 | Pediatr Crit Care Med | View High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators | Researchers | Clinical research |
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage | Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD | 2015 | Am J Hematol | View Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage | Researchers | Basic research |
Label-free assessment of red blood cell storage lesions by deep learning | Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE | 2018 | bioRxiv | View Label-free assessment of red blood cell storage lesions by deep learning | Researchers | New or improved product or process |
Mechanisms of platelet recovery in ITP associated with therapy | Pang SJY, Lazarus AH | 2010 | Ann Hematol | View Mechanisms of platelet recovery in ITP associated with therapy | Researchers | Basic research |
Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype | Berardi P, Cote J, Clarke G, Scalia V, Liwski R, Goldman M | 2017 | Transfusion | View Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype | Researchers | New or improved product or process |
Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration | Branch DR | 2011 | Future Virol | View Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration | Researchers | Basic research |
Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease | Kanias T, Sinchar D, Osei-Hwedieh D, Baust JJ, Jordan A, Zimring JC, Waterman HR, de Wolski KS, Acker JP, Gladwin MT | 2016 | Transfusion | View Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease | Researchers | Basic research |
Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use | Lin Y, Cohen R, Armali C, Callum J, Cserti-Gazdewich C, Lieberman L, Pendergrast J | 2018 | Vox Sang | View Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use | Researchers | Clinical research |
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. | Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA | 2018 | Blood Adv | View Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. | Researchers | Basic research |
Microvascular Thrombosis and Ischaemic Limb Losses in Critically Ill Patients | Warkentin TE | 2019 | Hämostaseologie | View Microvascular Thrombosis and Ischaemic Limb Losses in Critically Ill Patients | Researchers | Clinical research |
Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment | Jahan S, Adam MK, Manesia JK, Doxtator E, Ben RN, Pineault N | 2020 | Transfusion | View Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment | Researchers | Basic research |
Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor | Nazy I, Elliott TD, Arnold DM | 2020 | Br J Haematol | View Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor | Researchers | Basic research |
A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium | Drews SJ, Lesley P, Detsky ME, Distefano L, Ilagan C, Mehta S, McGeer A, Shehata N, Skeate R, Ramirez-Arcos S | 2020 | Transfusion | View A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium | Researchers | Basic research |
Evaluation of the effect of T regulatory cell depletion and donor BCG vaccination on Mycobacterium tuberculosis H37Ra infection using an in vitro model of human PBMC infection | Bhavanam S, Rayat GR, Keelan M, Kunimoto D, Drews SJ | 2020 | Pathog Dis | View Evaluation of the effect of T regulatory cell depletion and donor BCG vaccination on Mycobacterium tuberculosis H37Ra infection using an in vitro model of human PBMC infection | Researchers | Basic research |
Insights Into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics | Hovey O, Pasha R, Lehmann Z, Pineault N | 2020 | Proteomics | View Insights Into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics | Researchers | Basic research |
The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia | Huynh A, Arnold DM, Smith JW, Elliott TD, Ivetic N, Kelton JG, Nazy I | 2020 | Thromb Res | View The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia | Researchers | Basic research |
Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis | Sklavounos AA, Lamanna J, Modi D, Gupta S, Mariakakis A, Callum J, Wheeler AR | 2021 | Clin Chem | View Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis | Researchers | New or improved product or process |
Vaccine-induced immune thrombotic thrombocytopenia | Klok FA, Pai M, Huisman MV, Makris M | 2022 | Lancet Haematol | View Vaccine-induced immune thrombotic thrombocytopenia | Researchers | Clinical research |
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses | Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N | 2021 | Vox Sang | View International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses | Researchers | Clinical research |
Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression | Bhullar KS, Nael MA, Elokely KM, Drews SJ, Wu J | 2022 | Pharmaceutics | View Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression | Researchers | Basic research |
Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case-control study in Canada | Ding Z, Sherlock M, Chan AKC, Zachos M | 2022 | Blood Coagul Fibrinolysis | View Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case-control study in Canada | Researchers | Clinical research |
Assessing unintentional creation of bias against men who have sex with men as a function of exposure to blood donor screening questionnaire: A national randomized controlled trial | Hofkirchner A, Kohut T, O'Brien SF, Fisher WA | 2022 | Transfusion | View Assessing unintentional creation of bias against men who have sex with men as a function of exposure to blood donor screening questionnaire: A national randomized controlled trial | Researchers | MSM research |
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ | 2023 | Viruses | View Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | Researchers | Clinical research |
Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay | Simard C, Fournier D, Pineault N, Trépanier P | 2022 | Cytotherapy | View Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay | Researchers | New or improved product or process |
A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Marjoram D, Cruz-Leal Y, Bernardo L, Lazarus AH | 2017 | ISBT Sci Ser | View A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Researchers | Basic research |
Anti-A and anti-B: what are they and where do they come from? | Branch DR | 2015 | Transfusion | View Anti-A and anti-B: what are they and where do they come from? | Researchers | Other |
Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Ramirez-Arcos S, Jenkins C, Sheffield W | 2017 | Vox Sang | View Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Researchers | Basic research |
Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide | Roy R, Vidal S, Briard JG, Shiao TC, Ben RN | 2015 | Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 | View Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide | Researchers | Basic research |
Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma | McCurdy TR, Bhakta V, Eltringham-Smith LJ, Gataiance S, Fox-Robichaud AE, Sheffield WP | 2011 | J Biomed Biotechnol | View Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma | Researchers | Basic research |