Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Solving the dilemma of prevention of red cell alloimmunization Branch DR 2012 Immunotherapy View Researchers Other
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ, Canadian Critical Care Trials Group 2012 PLoS One View Researchers Clinical research
The cell motility modulator Slit2 is a potent inhibitor of platelet function Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA 2012 Circulation View Researchers Basic research
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G 2012 PLoS One View Researchers Basic research
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage Ali H, Rood IG, de Korte D, Ramirez-Arcos S 2012 Transfusion View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research
A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia Arnold DM, Kukaswadia S, Nazi I, Esmail A, Dewar L, Smith JW, Warkentin TE, Kelton JG 2013 J Thromb Haemost View Health care providers Clinical research
Bacterial growth in red blood cell units exposed to uncontrolled temperatures: challenging the 30-minute rule Ramirez-Arcos S, Perkins H, Kou Y, Mastronardi C, Kumaran D, Taha M, Yi QL, McLaughlin N, Kahwash E, Lin Y, Acker J 2013 Vox Sang View Regulators New or improved product or process
Evaluating the 4-hour and 30-minute rules: effects of room temperature exposure on red blood cell quality and bacterial growth Ramirez-Arcos S, Mastronardi C, Perkins H, Kou Y, Turner T, Mastronardi E, Hansen A, Yi QL, McLaughlin N, Kahwash E, Lin Y, Acker J 2013 Transfusion View Regulators New or improved product or process
FcgRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Nazi I, Arnold DM, Smith JW, Horsewood P, Moore JC, Warkentin TE, Crowther MA, Kelton JG 2013 J Thromb Haemost View Researchers Basic research
Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia Li C, Chen P, Vadasz B, Ma L, Zhou H, Lang S, Freedman J, Ni H 2013 Thromb Haemost View Researchers Basic research
Quality of red blood cells washed using the ACP 215 cell processor: assessment of optimal pre- and postwash storage times and conditions Hansen A, Yi QL, Acker JP 2013 Transfusion View Researchers New or improved product or process
Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness Arnold DM, Lauzier F, Rabbat C, Zytaruk N, Barlow Cash B, Clarke F, Heels-Ansdell D, Guyatt G, Walter SD, Davies A, Cook DJ, PROTECT Investigators on behalf of the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Clinical Trials Group 2013 Thromb Res View Researchers Clinical research
Challenges in the management of the blood supply Williamson LM, Devine DV 2013 Lancet View Blood operators Other
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
Legal Aspects of the Blood System in Canada Reis NM 2013 Public Health Law and Policy in Canada View Other Other
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada Fearon MA, Scalia V, Huang M, Dines I, Ndao M 2013 Can J Infect Dis Med Microbiol View Health care providers Clinical research
Positioning new treatments in the management of immune thrombocytopenia Arnold DM 2013 Pediatr Blood Cancer View Researchers Clinical research
Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway Crow AR, Yu H, Han D, Lazarus AH 2013 PLoS One View Researchers Basic research
Donor hemovigilance Goldman M 2013 Blood Transfus View Health care providers Other
Expert approaches to common bleeding and thrombotic problems, part II Hayward CP, Webert KE 2013 Semin Thromb Hemost View Health care providers Other
Research with Blood Donated to Blood Banking Organizations Reis NM 2013 Health Law Review View Other Other
Utility of cross-matched platelet transfusions in patients with hypoproliferative thrombocytopenia: a systematic review Vassallo RR, Fung M, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation Evaluation for Transfusion Therapies Collaborators 2013 Transfusion View Researchers Clinical research
A platelet cover-up Arnold DM 2013 Blood View Researchers Other
Legal Foundations of Public Health Law Reis NM 2013 Public Health Law and Policy in Canada View Other Other
Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles Bicalho B, Holovati JL, Acker JP 2013 Biochim Biophys Acta View Researchers Basic research
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Boyle AJ, Roddick LA, Bhakta V, Lambourne MD, Junop MS, Liaw PC, Weitz JI, Sheffield WP 2013 BMC Biochem View Researchers Basic research
Alloimmunization of patients by blood units harboring distinct DEL variants St-Louis M, Lebrun A, Goldman M, Lavoie M 2013 Immunohematology View Health care providers Clinical research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Identifying D-positive donors using a second automated testing platform Goldman M, Resz I, Cote J, Ochoa G, Angus N 2013 Immunohematology View Blood operators New or improved product or process
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
ResearchUnit: Should patients receive HLA-selected platelets? Shehata N 2013 Blood.ca website View Other Other
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
ResearchUnit: Doubling the 30-minute rule without compromising Red Blood Cells quality and safety. Ramirez-Arcos S 2013 Blood.ca website View Other Other
Thrombocytopenia in the critically ill Shehata N, Fontes ML 2013 Can J Anaesth View Researchers Other
Allowing blood donation from men who had sex with men more than 5 years ago: a model to evaluate the impact on transfusion safety in Canada Germain M, Robillard P, Delage G, Goldman M 2013 Vox Sang View Blood operators New or improved product or process
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Posttransplant monitoring of de novo human leukocyte antigen donor-specific antibodies in kidney transplantation Wiebe C, Nickerson P 2013 Curr Opin Organ Transplant View Health care providers Clinical research
Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Ghadaki B, Nazi I, Kelton JG, Arnold DM 2013 Transfusion View Health care providers Clinical research
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other