Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR 2020 Transfusion View Researchers Basic research
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP, The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion Collaborative 2019 Vox Sang View Researchers Benchmarking and standard setting
Canada's MSM Research Program - producing and mobilizing knowledge Chargé S, Haw J 2020 Transfusion Today Researchers MSM research
Emerging use of machine learning and advanced technologies to assess red cell quality Sebastian JA, Kolios MC, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Objective assessment of stored blood quality by deep learning Doan M, Sebastian JA, Caicedo JC, Siegert S, Roch A, Turner TR, Mykhailova O, Pinto RN, McQuin C, Goodman A, Parsons MJ, Wolkenhauer O, Hennig H, Singh S, Wilson A, Acker JP, Rees P, Kolios MC, Carpenter AE 2020 PLoS Pathog View Researchers New or improved product or process
Research Unit: Machine learning throws away the buckets to better understand red blood cell quality Acker JP 2020 Blood.ca website View Researchers Basic research
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri Ramirez-Arcos S 2020 Ann Blood View Researchers Clinical research
High sub-zero organ preservation: A paradigm of nature-inspired strategies William N, Acker JP 2021 Cryobiology View Researchers Basic research
Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F, Baltrus DA 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia Huang CT, Hsu SY, Wang CH, Tseng WJ, Yang CY, Ng CJ, Warkentin TE, Cheng MH 2021 Thromb Res View Researchers Clinical research
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N 2022 Transfusion View Researchers Clinical research
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B 2022 J Infect Dis View Researchers Clinical research
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Basic research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Biomaterials View Researchers Basic research
Adhesion Molecules. Ni H 2013 Mechanisms in Hematology View Researchers Basic research
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang View Researchers Basic research
ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2013 Chem Commun View Researchers Basic research
Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis Husseinzadeh HD, Gimotty PA, Pishko AM, Buckley M, Warkentin TE, Cuker A 2017 J Thromb Haemost View Researchers Clinical research
Ebola virus VP35 blocks stress granule assembly Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ 2017 Virology View Researchers Basic research
Epigenetic regulation of endothelial-cell-mediated vascular repair Fraineau S, Palii CG, Allan DS, Brand M 2015 FEBS J View Researchers Other
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution Johnson L, Schubert P, Tan S, Devine DV, Marks DC 2015 Transfusion View Researchers Basic research
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF 2015 Appl Spectrosc View Researchers Basic research
How do I interpret a p value? O'Brien SF, Osmond L, Yi Q-L 2015 Transfusion View Researchers Other
Impact of ethnicity on human umbilical cord blood banking: a systematic review Akyurekli C, Chan JY, Elmoazzen H, Tay J, Allan DS 2014 Transfusion View Researchers Clinical research
Innate immunity as orchestrator of stem cell mobilization Ratajczak MZ, Kim CH, Wojakowski W, Janowska-Wieczorek A, Kucia M, Ratajczak J 2010 Leukemia View Researchers Basic research
Megakaryopoiesis and ex vivo differentiation of stem cells into megakaryocytes and platelets Pineault N, Boisjoli GJ 2015 ISBT Sci Ser View Researchers Basic research
Monoclonal versus polyclonal anti-D in the treatment of ITP Lazarus AH 2013 Expert Opin Biol Ther View Researchers Basic research
On-chip PCR amplification of genomic and viral templates in unprocessed whole blood Manage DP, Morrissey YC, Stickel AJ, Lauzon J, Atrazhev A, Acker JP, Pilarski LM 2011 Microfluid Nanofluidics View Researchers New or improved product or process
Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin Scott BM, Matochko WL, Gierczak RF, Bhakta V, Derda R, Sheffield WP 2014 PLoS One View Researchers Basic research
Platelet-activating antibodies are detectable at the earliest onset of heparin-induced thrombocytopenia, with implications for the operating characteristics of the serotonin-release assay Warkentin TE, Arnold DM, Kelton JG, Sheppard JI, Smith JW, Nazy I 2018 Chest View Researchers Clinical research
Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM 2018 Transfusion View Researchers New or improved product or process
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ, Canadian Critical Care Trials Group 2012 PLoS One View Researchers Clinical research
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
The cell motility modulator Slit2 is a potent inhibitor of platelet function Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA 2012 Circulation View Researchers Basic research
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F 2014 J Immunol View Researchers Basic research
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G 2012 PLoS One View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2018 Industrial Engineering and Operations Management I View Researchers Clinical research
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S 2018 Transfusion View Researchers Other
GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out Lewis BJB, Leontyev D, Neschadim A, Blacquiere M, Branch DR 2018 Clin Exp Immunol View Researchers Basic research
ResearchUnit: Plasma: what's in the bag? Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
Ironing out frequent blood donation Devine DV 2019 Lancet Haematol View Researchers New or improved product or process
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype Almizraq R, Kipkeu B, Acker JP 2020 Transfusion View Researchers Basic research
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR 2020 Artificial Intelligence in Medicine View Researchers New or improved product or process
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM 2021 Transfusion View Researchers Clinical research