Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes Bernardo L, Denomme GA, Shah K, Lazarus AH 2014 Adv Hematol View Researchers Basic research
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage Li J, Callum JL, Lin Y, Zhou Y, Zhu G, Ni H 2014 Haematologica View Researchers Clinical research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
45 - Alloimmune Thrombocytopenia Kaplan C, Bertrand G, Ni H 2019 Platelets (Fourth Edition) View Researchers New or improved product or process
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Evaluation of a hydrogel-based diagnostic approach for the point-of-care based detection of Neisseria gonorrhoeae Perera S, Taheri A, Khan N, Parti R, Stefura S, Skiba P, Acker J, Martin I, Kusalik A, Dillon J-A 2018 Antibiotics View Researchers New or improved product or process
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains Spitalnik SL, Devine DV 2019 Transfusion View Researchers Other
Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics Yang X, Kang N, Toyofuku WM, Scott MD 2018 Immunobiology View Researchers Basic research
Concentré de recherche: Améliorer les analyses de qualité réalisées sur les cellules souches destinées à la greffe Pineault N 2020 Blood.ca website View Researchers New or improved product or process
Gay and bisexual men’s views on reforming blood donation policy in Canada: a qualitative study Grace D, Gaspar M, Lessard D, Klassen B, Brennan DJ, Adam BD, Jollimore J, Lachowsky NJ, Hart TA 2019 BMC Public Health View Researchers Other
Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings Yazer MH, Spinella PC, Doyle L, Kaufman RM, Dunn R, Hess JR, Filho LA, Fontaine M, Gathof B, Jackson B, Murphy MF, Pasion J, Raval JS, Rosinski K, Seheult J, Shih AW, Sperry J, Staves J, Tuott EE, Ziman A, Triulzi DJ, Biomedical Excellence for Safer Transfusion Collaborative 2020 Anesthesiology View Researchers Clinical research
Biological Modulation of the Treg:Teff Ratio: From Immunosuppression to Immunoactivation Yang X, Scott M 2020 Immunosupression View Researchers Basic research
Differential red blood cell age fractionation and Band?3 phosphorylation distinguish two different subtypes of warm autoimmune hemolytic anemia Bloch EM, Branch HA, Sakac D, Leger RM, Branch DR 2020 Transfusion View Researchers Basic research
Management of heparin-induced thrombocytopenia: systematic reviews and meta-analyses Morgan RL, Ashoorion V, Cuker A, Begum H, Ross S, Martinez N, Chong BH, Linkins LA, Warkentin TE, Wiercioch W, Nieuwlaat R, Schünemann H, Santesso N 2020 Blood Adv View Researchers Clinical research
Tantalum-containing meso-porous glass fibres for hemostatic applications Nagrath M, Rahimnejad Yazdi A, Rafferty A, Daly D, Rahman SU, Gallant RC, Ni H, Arany PR, Towler MR 2021 Mater Today Commun View Researchers Basic research
Genome Sequence of Staphylococcus aureus Strain CBS2016-05, Isolated from Contaminated Platelet Concentrates in Canada Yousuf B, Flint A, Weedmark K, Pagotto F, Ramirez-Arcos S, Hotopp JCD 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study Razatos A, Acker JP, de Korte D, Bégué S, Noorman F, Doyle B, Zia M, Min K, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Researchers New or improved product or process
Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma Ma Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L 2021 Langmuir View Researchers Basic research
A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations Jiang D, Lim W, Crowther M, Garcia D 2021 Blood Adv View Researchers Clinical research
International survey of strategies to mitigate transfusion-transmitted Trypanosoma cruzi in non-endemic countries, 2016–2018 Crowder LA, Wendel S, Bloch EM, O'Brien SF, Delage G, Sauleda S, Leiby DA, for the WP-TTID Subgroup on Parasites 2022 Vox Sang View Researchers Benchmarking and standard setting
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial Bégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair M-C, Cerro S, Avram M, Arnold DM 2021 Trials View Researchers Clinical research
(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus Almizraq RJ, Frias Boligan K, Loriamini M, McKerlie C, Branch DR 2022 Front Immunol View Researchers Basic research
Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia Giles JB, Steiner HE, Rollin J, Shaffer CM, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle NM, Kubo M, Miller EC, Martinez KL, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM, Karnes JH 2022 Blood Adv View Researchers Basic research
Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM 2017 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K 2014 Radiology View Researchers Basic research
Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer Siren EM, Singh S, Kluger R 2015 Org Biomol Chem View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Determining the inventory impact of extended shelf life platelets with a network simulation model Blake J 2017 Transfusion View Researchers New or improved product or process
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Immunocamouflage: The biophysical basis of immunoprotection by grafted methoxypoly(ethylene glycol) (mPEG) Le Y, Scott MD 2010 Acta Biomater View Researchers Basic research
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers Wang A, Kluger R 2014 Biochemistry View Researchers Basic research
Mitochondrial damage-associated molecular patterns in blood transfusion products Marcoux G, Boilard E 2017 ISBT Sci Ser View Researchers Basic research
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) Zufferey A, Kapur R, Semple J 2017 J Clin Med View Researchers Basic research
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS View Researchers Basic research
Quality of red blood cells washed using an automated cell processor with and without irradiation Hansen AL, Turner TR, Yi QL, Acker JP 2014 Transfusion View Researchers New or improved product or process
Reply to: Short-Term versus Long-Term Blood Storage Heddle N 2017 N Engl J Med View Researchers Other
TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM 2014 Blood View Researchers Basic research
The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice Eltringham-Smith LJ, Lei X, Reheman A, Lambourne MD, Pryzdial EL, Ni H, Sheffield WP 2014 Transfusion View Researchers Basic research
The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis Du C, Mendelson AA, Guan Q, Chapanian R, Chafeeva I, da Roza G, Kizhakkedathu JN 2014 Biomaterials View Researchers Basic research
Using simulation to evaluate a blood supply network in the Canadian maritime provinces Blake J, Hardy M 2013 J Enterp Inf Manag View Researchers New or improved product or process
Concentré de recherche : Une façon nouvelle d'évaluer la qualité des globules rouges Acker J 2018 Blood.ca website View Researchers Clinical research
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT Krauel K, Preuße P, Warkentin TE, Trabhardt C, Brandt S, Jensch I, Mandelkow M, Hammer E, Hammerschmidt S, Greinacher A 2018 Blood View Researchers Basic research
The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test Vrbensky JR, Moore JE, Arnold DM, Smith JW, Kelton JG, Nazy I 2019 J Thromb Haemost View Researchers Clinical research
Assessing the Vascular Deformability of Erythrocytes and Leukocytes: From Micropipettes to Microfluidics Scott M, Mathews K, Ma H 2019 Current and Future Aspects of Nanomedicine View Researchers Basic research
Deformability based sorting of stored red blood cells reveals donor-dependent aging curves Islamzada E, Matthews K, Guo Q, Santoso AT, Duffy SP, Scott MD, Ma H 2020 Lab Chip View Researchers Basic research
The impact of age and sex on first-time donor return behavior Masser BM, Wright S, Germain M, Grégoire Y, Goldman M, O'Brien SF, Kamel H, Bravo M, Merz EM, van den Hurk K, Prinsze F, Takanashi M, Wilder Z, Shaz B, Biomedical Excellence for Safer Transfusion (BEST) Collaborative 2020 Transfusion View Researchers Clinical research
A Canadian perspective on the use and preparation of cryopreserved red cell concentrates Turner TR, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process