Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model Arbaeen AF, Schubert P, Sheffield WP, Devine DV 2021 Transfusion View Researchers New or improved product or process
Prevention of transfusion-transmitted syphilis by blood operators: How much is enough when transfusion-transmission has not been identified for decades? Drews SJ 2021 Transfusion View Blood operators Benchmarking and standard setting
Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates Li W, William N, Acker JP 2023 Transfusion View Researchers Basic research
How do we decide how representative our donors are for public health surveillance? O'Brien SF, Drews SJ, Lewin A, Russell A, Davison K, Goldman M, International Society for Blood Transfusion Transfusion Transmitted Infectious Disease Working Party Surveillance Risk Assessment Policy Sub-group 2022 Transfusion View Researchers Benchmarking and standard setting
Cold-stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry Zhao HQ, Serrano K, Culibrk B, Chen Z, Devine DV 2022 Transfusion View Researchers New or improved product or process
Changes in blood center red blood cell distributions in the era of patient blood management: the trends for collection (TFC) study Yazer MH, Jackson B, Beckman N, Chesneau S, Bowler P, Delaney M, Devine D, Field S, Germain M, Murphy MF, Sayers M, Shaz B, Shinar E, Takanashi M, Vassallo R, Wickenden C, Yahalom V, Land K, on behalf of the BEST Collaborative 2016 Transfusion View Blood operators New or improved product or process
Internal medicine resident knowledge of transfusion medicine: results from the BEST-TEST international education needs assessment Haspel RL, Lin Y, Mallick R, Tinmouth A, Cid J, Eichler H, Lozano M, van de Watering L, Fisher PB, Ali A, Parks E 2014 Transfusion View Health care providers Other
Optimal conditions for the performance of a monocyte monolayer assay Tong TN, Burke-Murphy E, Sakac D, Pendergrast J, Cserti-Gazdewich C, Laroche V, Branch DR 2016 Transfusion View Researchers Basic research
Residual risk of bacterial contamination of platelets: six years of experience with sterility testing Ramirez-Arcos S, DiFranco C, McIntyre T, Goldman M 2017 Transfusion View Researchers New or improved product or process
Transfusion-related lung injury in children: a case series and review of the literature Lieberman L, Petraszko T, Yi QL, Hannach B, Skeate R 2014 Transfusion View Health care providers Clinical research
Modeling rare blood in Canada Blake JT, Clarke G 2018 Transfusion View Health care providers New or improved product or process
Isoagglutinin-reduced immunoglobulin retains efficacy in mouse models of immune thrombocytopenia and rheumatoid arthritis and is less likely to cause intravenous immunoglobulin–associated hemolysis Cen SY, Branch DR 2020 Transfusion View Researchers Basic research
Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing Tremblay T, Branch DR, Loubaki L 2020 Transfusion View Researchers New or improved product or process
Five novel FY null alleles associated with typing discrepancies Vege S, Floch A, Lomas-Frances C, Clarke G, Westhoff CM 2021 Transfusion View Researchers Benchmarking and standard setting
Rejuvenated and safe: Freeze-dried plasma for the 21st century Sheffield WP, V. Devine D 2022 Transfusion View Health care providers New or improved product or process
Implementation of measures to reduce vasovagal reactions: Donor participation and results Goldman M, Uzicanin S, Marquis-Boyle L, O'Brien SF 2021 Transfusion View Health care providers Clinical research
Bacterial screening of outdated buffy coat platelet pools using a culture system and a rapid immunoassay Ramirez-Arcos S, Kou Y, Mastronardi C, Perkins H, Goldman M 2011 Transfusion View Blood operators New or improved product or process
p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment Chen Z, Schubert P, Culibrk B, Devine DV 2014 Transfusion View Researchers Basic research
Plasma transfusion trials and tribulations Shih A, Arnold DM 2015 Transfusion View Health care providers Clinical research
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin Branch DR, Scofield TL, Moulds JJ, Swanson JL 2011 Transfusion View Researchers Basic research
Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency Goldman M, Yi Q-L, Steed T, O'Brien SF 2019 Transfusion View Researchers New or improved product or process
Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity Mykhailova O, Olafson C, Turner TR, D?Alessandro A, Acker JP 2020 Transfusion View Researchers Basic research
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H 2022 Transfusion View Researchers Basic research
An evaluation of the clinical impacts of 7-day platelets Ning S, Gabarin N, Li N, Liu Y, Lucier K, Barty R, Acker J, Webert KE, Warkentin TE, Arnold DM, Heddle NM 2023 Transfusion View Researchers Clinical research
Donor iron policy: from research to practice O'Brien SF 2016 Transfusion View Researchers New or improved product or process
Risks and trends of red blood cell transfusion in obstetric patients: a retrospective study of 45,213 deliveries using administrative data Shehata N, Chassé M, Colas JA, Murphy M, Forster AJ, Malinowski AK, Ducharme R, Fergusson DA, Tinmouth A, Wilson K 2017 Transfusion View Health care providers Clinical research
The Stem Cell Club: a model for unrelated stem cell donor recruitment Fingrut W, Parmar S, Cuperfain A, Rikhraj K, Charman E, Ptak E, Kahlon M, Graham A, Luong S, Wang YG, Yu J, Arora N, Suppiah R, Li EW, Lee A, Welsh C, Benzaquen M, Thatcher A, Baharmand I, Ladd A, Petraszko T, Allan D, Messner H 2017 Transfusion View Health care providers New or improved product or process
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process
Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation Wang A, Singh S, Yu B, Bloch DB, Zapol WM, Kluger R 2019 Transfusion View Researchers Basic research
Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing Taha M, Kyluik-Price D, Kumaran D, Scott MD, Toyofuku W, Ramirez-Arcos S 2019 Transfusion View Researchers Basic research
Could antigen loss be a potential mechanism to explain antibody-mediated immune suppression? Cruz-Leal Y, Lazarus AH 2021 Transfusion View Researchers Basic research
Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada Turner TR, Olafson C, Mykhailova O, Xu A, Acker JP 2020 Transfusion View Researchers New or improved product or process
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion Heddle NM, Cardoso M, van der Meer PF 2020 Transfusion View Researchers Clinical research
Sexual risk behavior questions: Understanding and mitigating donor discomfort Haw J, Woo H, Kohut T, Fisher W 2022 Transfusion View Blood operators MSM research
Alternatives to blood donor deferral of gay, bisexual, and other men who have sex with men: Acceptability of screening the sexual risk behavior of all blood donors Fisher WA, Kohut T, Woo H, Haw J 2023 Transfusion View Blood operators MSM research
Changes in coagulation factor activity and content of di(2-ethylhexyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawing Sheffield WP, Bhakta V, Mastronardi C, Ramirez-Arcos S, Howe D, Jenkins C 2012 Transfusion View Health care providers New or improved product or process
Optimal transfusion practices after allogeneic hematopoietic cell transplantation: a systematic scoping review of evidence from randomized controlled trials Christou G, Iyengar A, Shorr R, Tinmouth A, Saidenberg E, Maze D, Tay J, Bredeson C, Allan DS 2016 Transfusion View Health care providers Clinical research
Selective testing for Trypanosoma cruzi: the first year after implementation at Canadian Blood Services O'Brien SF, Scalia V, Goldman M, Fan W, Yi QL, Dines IR, Huang M, Ndao M, Fearon MA 2012 Transfusion View Blood operators New or improved product or process
Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM 2018 Transfusion View Researchers Clinical research
Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation Turner TR, Lautner L, Hill A, Howell A, Skeate R, Acker JP 2020 Transfusion View Researchers Basic research
Potentially clinically significant anti-Dib identified by monocyte monolayer assay before transfusion Branch DR, Holton MB, Ison T, Cote J, Dube C, Lau W 2021 Transfusion View Researchers Basic research
The utility of a monocyte monolayer assay in the assessment of intravenous immunoglobulin–associated hemolysis Tong TN, Blacquiere M, Sakac D, Burke-Murphy E, Yi Q, Callum J, Cserti-Gazdewich C, Parmar N, Shehata N, Pavenski K, Lau W, Lin Y, Lieberman L, Branch DR, Pendergrast J 2020 Transfusion View Researchers New or improved product or process
Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy Vardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB 2021 Transfusion View Researchers New or improved product or process
Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV 2022 Transfusion View Researchers Basic research
How do I think about blood donor eligibility criteria for medical conditions? Goldman M 2021 Transfusion View Researchers Benchmarking and standard setting
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
Paroxysmal cold hemoglobinuria: a difficult diagnosis in adult patients Zeller MP, Arnold DM, Al Habsi K, Cserti-Gazdewich C, Delage G, Lebrun A, Heddle NM 2017 Transfusion View Health care providers Clinical research