Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ 2016 Syst Rev View Researchers Basic research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Introduction to the special issue: Teaching healthcare operations research, part 2 Blake J 2017 INFORMS Transactions on Education View Researchers New or improved product or process
Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia Zhou H, Hou Y, Liu X, Qiu J, Feng Q, Wang Y, Zhang X, Min Y, Shao L, Liu X, Li G, Li L, Yang L, Xu S, Ni H, Peng J, Hou M 2015 Thromb Haemost View Researchers Basic research
Microparticles as biomarkers of lung disease - enumeration in biological fluids using lipid bilayer microspheres McVey MJ, Spring C, Semple JW, Maishan M, Kuebler WM 2016 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment Chen Z, Schubert P, Culibrk B, Devine DV 2014 Transfusion View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins Sheffield WP, Eltringham-Smith LJ, Bhakta V, Gataiance S 2012 Thromb Haemost View Researchers Basic research
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL Evren S, Ma XZ, Sakac D, Branch DR 2012 Exp Hematol View Researchers Basic research
Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 J Gene Med View Researchers Basic research
The procoagulant envelope virus surface: contribution to enhanced infection Pryzdial EL, Sutherland MR, Ruf W 2014 Thromb Res View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin Branch DR, Scofield TL, Moulds JJ, Swanson JL 2011 Transfusion View Researchers Basic research
Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency Goldman M, Yi Q-L, Steed T, O'Brien SF 2019 Transfusion View Researchers New or improved product or process
The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A 2018 Clin Biochem View Researchers Basic research
Synthesis of Highly Biocompatible and Temperature-Responsive Physical Gels for Cryopreservation and 3D Cell Culture Nagao M, Sengupta J, Diaz-Dussan D, Adam M, Wu M, Acker J, Ben R, Ishihara K, Zeng H, Miura Y, Narain R 2018 ACS Appl Bio Mater View Researchers Basic research
Transfusion-related acute lung injury (TRALI) Petraszko T 2019 Blood.ca website View Researchers Clinical research
Virus envelope tissue factor promotes infection in mice Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG 2019 J Thromb Haemost View Researchers Basic research
Implications of variability in cell membrane permeability for design of methods to remove glycerol from frozen-thawed erythrocytes Lahmann JM, Sanchez CC, Benson JD, Acker JP, Higgins AZ 2020 Cryobiology View Researchers Basic research
Stability of 40 cytokines/chemokines in chronically ill patients under different storage conditions Binnington B, Sakac D, Yi Q, Tong TN, Parmar N, Duong TT, Yeung RSM, Pendergrast J, Branch DR 2020 Cytokine View Researchers Basic research
50 years of Vox Sanguinis International Forums Lozano M, Dunbar NM, Devine DV 2020 Vox Sang View Researchers Benchmarking and standard setting
Could antigen loss be a potential mechanism to explain antibody-mediated immune suppression? Cruz-Leal Y, Lazarus AH 2021 Transfusion View Researchers Basic research
Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada Turner TR, Olafson C, Mykhailova O, Xu A, Acker JP 2020 Transfusion View Researchers New or improved product or process
Industry, experts and the role of the ‘invisible college’ in the dissemination of non-invasive prenatal testing in the US Holloway K, Miller FA, Simms N 2021 Soc Sci Med View Researchers Ethical, legal and social implications research
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion Heddle NM, Cardoso M, van der Meer PF 2020 Transfusion View Researchers Clinical research
Transient warming affects potency of cryopreserved cord blood units Pasha R, Howell A, Turner TR, Halpenny M, Elmoazzen H, Acker JP, Pineault N 2020 Cytotherapy View Researchers New or improved product or process
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M 2022 Sci Transl Med View Researchers Clinical research
Meta-Analysis of Risk of Vaccine-Induced Immune Thrombotic Thrombocytopenia Following ChAdOx1-S Recombinant Vaccine Chan BT, Bobos P, Odutayo A, Pai M 2021 medRxiv View Researchers Clinical research
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP 2021 Transfus Med Hemotherapy View Researchers Clinical research
Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency Bahabri A, Moffat KA, Carlino SA, Chan AKC, Bhatt MD 2022 Int J Lab Hematol View Researchers Basic research
Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner De Silva E, Devine DV, Jan E, Roskelley CD, Kim H 2022 Biochem J View Researchers Basic research
Model of Acute Liver Failure in an Isolated Perfused Porcine Liver—Challenges and Lessons Learned Hefler J, Hatami S, Thiesen A, Olafson C, Durand K, Acker J, Karvellas CJ, Bigam DL, Freed DH, Shapiro AMJ 2022 Biomedicines View Researchers New or improved product or process
An evaluation of the clinical impacts of 7-day platelets Ning S, Gabarin N, Li N, Liu Y, Lucier K, Barty R, Acker J, Webert KE, Warkentin TE, Arnold DM, Heddle NM 2023 Transfusion View Researchers Clinical research
Coagulation and complement: Key innate defense participants in a seamless web Pryzdial ELG, Leatherdale A, Conway EM 2022 Front Immunol View Researchers Basic research
ResearchUnit: Evaluating infusion pump safety for red blood cell transfusions Wolfe A 2022 Blood.ca website View Researchers Benchmarking and standard setting
An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches Acker JP, Croteau IM, Yi QL 2012 Clin Chim Acta View Researchers New or improved product or process
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
Donor iron policy: from research to practice O'Brien SF 2016 Transfusion View Researchers New or improved product or process
Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions Rossi NAA, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN 2010 J Am Chem Soc View Researchers Basic research
Fluids in sepsis and septic shock (FISSH): protocol for a pilot randomised controlled trial Rochwerg B, Millen T, Austin P, Zeller M, D'Aragon F, Jaeschke R, Masse MH, Mehta S, Lamontagne F, Meade M, Guyatt G, Cook DJ 2017 BMJ Open View Researchers Clinical research
Hepatoprotective effects of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] on alcohol-damaged primary rat hepatocyte culture in vitro Jiang W, Bian Y, Wang Z, Chang TMS 2016 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells Chapanian R, Constantinescu I, Rossi NA, Medvedev N, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H 2010 Cancer Biol Ther View Researchers Basic research
Nouvelle cuisine: platelets served with inflammation Kapur R, Zufferey A, Boilard E, Semple JW 2015 J Immunol View Researchers Basic research
Targeting activated platelets and fibrinolysis: hitting two birds with one stone Reheman A, Xu X, Reddy EC, Ni H 2014 Circ Res View Researchers Basic research
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process
Anti-M (French) Clarke G, Cote J, Lane D 2018 Blood.ca website View Researchers Basic research