Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion View Researchers Clinical research
The epidemiology of multicomponent blood transfusion: a systematic review Perelman I, Khair S, Dermer E, Tinmouth A, Saidenberg E, Fergusson D 2019 Transfus Med View Researchers Clinical research
Donneurs de sang total avec anticorps Yan M 2019 Blood.ca website View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
Timeline of heparin-induced thrombocytopenia seroconversion in serial plasma samples tested using an automated latex immunoturbidimetric assay Warkentin TE, Sheppard J-AI, Smith JW, Arnold DM, Nazy I 2019 Int J Lab Hematol View Researchers New or improved product or process
Cluster-randomized trials in transfusion medicine Sirotich E, Barty R, Li N, Arnold DM 2020 Transfusion View Researchers Clinical research
Development of an Ordinal Scale Treatment Endpoint for Adults Hospitalized With Influenza Lee N, Smith SW, Hui DSC, Ye M, Zelyas N, Chan PKS, Drews SJ, Zapernick L, Wong R, Labib M, Shokoples S, Eurich DT 2020 Clin Infect Dis View Researchers Clinical research
Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens AP, Palumbo J, Conway EM, Pryzdial EL, Cullis P, Kastrup CJ 2020 Blood View Researchers Basic research
Current challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed C, Steele W, Davidson K, Custer B, O’Brien S, Assessment ObotSR, Policy sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2021 medRxiv View Researchers Basic research
CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM 2021 J Thromb Haemost View Researchers Basic research
Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada Brennan D, Armstrong JP, Kesler M, Bekele T, Lachowksy N, Grace D, Hart TA, Souleymanov R, Adam B 2023 PLOS Glob Public Health View Researchers MSM research
Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature Germini F, Noronha N, Abraham Philip B, Olasupo O, Pete D, Navarro T, Keepanasseril A, Matino D, de Wit K, Parpia S, Iorio A 2022 J Thromb Haemost View Researchers Clinical research
Clinical and laboratory predictors of fetal and neonatal alloimmune thrombocytopenia Matusiak K, Patriquin CJ, Deniz S, Dzaja N, Smith JW, Wang G, Nazy I, Kelton JG, Arnold DM 2022 Transfusion View Researchers Clinical research
Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism Tran A, Yan MTS, Branch DR, Blacquiere M, Pineault N, Pasha R, Clarke G 2023 Transfusion View Researchers Clinical research
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP) Kapur R, Catalina MD, Aslam R, Speck ER, Francovitch RF, Semple JW 2017 Br J Haematol View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
Cancer and platelet crosstalk: opportunities and challenges for aspirin and other anti-platelet agents Xu XR, Yousef GM, Ni H 2018 Blood View Researchers Basic research
Concentré de recherche: Vers une uniformisation des politiques d'exclusion du don de sang et de plasma Goldman M, O'Brien S, Devine D 2018 Blood.ca website View Researchers Basic research
Fibronectin orchestrates thrombosis and hemostasis Wang Y, Carrim N, Ni H 2015 Oncotarget View Researchers Other
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O'Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS 2016 Lancet View Researchers Clinical research
Pathogen inactivation treatment of plasma and platelet concentrates and their predicted functionality in massive transfusion protocols Arbaeen AF, Schubert P, Serrano K, Carter CJ, Culibrk B, Devine DV 2017 Transfusion View Researchers Basic research
Platelet immunobiology: platelets as prey and predator Kapur R, Semple JW 2018 ISBT Sci Ser View Researchers Basic research
Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature Zhurova M, Akabutu J, Acker J 2012 J Blood Transfus View Researchers New or improved product or process
Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts Neschadim A, Pritzker LB, Pritzker KP, Branch DR, Summerlee AJ, Trachtenberg J, Silvertown JD 2014 Endocr Relat Cancer View Researchers Basic research
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD 2018 Can J Kidney Health Dis View Researchers Clinical research
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN 2016 ACS Omega View Researchers Basic research
T Regulatory Cells and Dendritic Cells Protect Against Transfusion-Related Acute Lung Injury via IL-10 Kapur R, Kim M, Aslam R, McVey MJ, Tabuchi A, Luo A, Liu J, Li Y, Shanmugabhavananthan S, Speck ER 2017 Blood View Researchers Basic research
The Fanconi Anemia Group C Protein Interacts with Uncoordinated 5A and Delays Apoptosis Huang F, Ben Aissa M, Magron A, Huard CC, Godin C, Levesque G, Carreau M 2014 PLoS One View Researchers Basic research
The role of glycosphingolipids in HIV/AIDS Lingwood CA, Branch DR 2011 Discov Med View Researchers Basic research
Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model Brinc D, Le-Tien H, Crow AR, Semple JW, Freedman J, Lazarus AH 2010 Transfusion View Researchers Basic research
Using Raman spectroscopy to assess hemoglobin oxygenation in red blood cell concentrate: an objective proxy for morphological index to gauge the quality of stored blood? Atkins CG, Schulze HG, Chen D, Devine DV, Blades MW, Turner RF 2017 Analyst View Researchers New or improved product or process
Paracrine Factors Released by Osteoblasts Provide Strong Platelet Engraftment Properties Abu-Khader A, Law KW, Jahan S, Manesia JK, Pasha R, Hovey O, Pineault N 2019 Stem Cells View Researchers Basic research
Initial flow cytometric evaluation of the Clearllab lymphoid screen Hedley BD, Cheng G, Luider J, Kern W, Lozanski G, Chin-Yee I, Lowes LE, Keeney M, Careaga D, Magari R, Tejidor L 2018 Cytometry B Clin Cytom View Researchers Basic research
Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J, International Collaboration for Transfusion Medicine Guidelines 2018 Vox Sang View Researchers Clinical research
Hemostatic efficacy of pathogen-inactivated versus untreated platelets: a randomized controlled trial van der Meer PF, Ypma PF, van Geloven N, van Hilten JA, van Wordragen-Vlaswinkel RJ, Eissen O, Zwaginga JJ, Trus M, Beckers EAM, te Boekhorst P, Tinmouth A, Lin Y, Hsia C, Lee D, Norris PJ, Goodrich RP, Brand A, Hervig T, Heddle NM, van der Bom JG, Kerkhoffs J-LH 2018 Blood View Researchers Clinical research
Alpha-Dystroglycan Supports Platelet Aggregation and Thrombus Formation Wang Y, Gallant RC, Neves MAD, Lei X, Gupta S, Coelho R, Wong T, Cohn RD, Campbell KP, Ni H 2019 Blood View Researchers Basic research
Defining certainty of net benefit: a GRADE concept paper Alper BS, Oettgen P, Kunnamo I, Iorio A, Ansari MT, Murad MH, Meerpohl JJ, Qaseem A, Hultcrantz M, Schunemann HJ, Guyatt G, GRADE Working Group 2019 BMJ Open View Researchers Clinical research
Human red blood cell stroma: an alternative to traditional allogeneic adsorption methods Wilson EM, Branch DR 2019 Transfusion View Researchers Basic research
A call for caution in use of pertussis vaccine effectiveness studies to estimate waning immunity: A Canadian Immunization Research Network Study Crowcroft NS, Schwartz KL, Savage RD, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Deeks SL, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Righolt CH, Bell C, Mahmud SM, Kwong JC 2020 Clin Infect Dis View Researchers Clinical research
The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low cost technique for ex vivo subnormothermic lung perfusion Lautner L, Himmat S, Acker JP, Nagendran J 2020 Cryobiology View Researchers Basic research
Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress Ariens R, Becattini C, Bender M, Bergmeier W, Castoldi E, Devreese K, Ellis M, Gailani D, Ignjatovic V, James PD, Kerrigan S, Lambert M, Lee LH, Levi M, Maugeri N, Meijers J, Melero-Martin J, Michelson AD, Mingozzi F, Neeves K, Ni H, Olsson A-K, Prohászka Z, Ranson M, Riva N, Senis Y, van Ommen CH, Vaughan DE, Weisel J 2020 J Thromb Haemost View Researchers Basic research
New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases Norris PAA, Kaur G, Lazarus AH 2020 Curr Opin Hematol View Researchers Basic research
The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study William N, Bicahlo B, Hansen A, de Korte D, Acker JP, Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Basic research
Necrotizing enterocolitis and mortality after transfusion of ABO non-identical blood Parvizian MK, Barty R, Heddle NM, Li N, McDougall T, Mukerji A, Fusch C, Solh Z 2021 Transfusion View Researchers Clinical research
Mechanism of increased efficacy of recombinant Fc-?TP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR 2021 eJHaem View Researchers Basic research
The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters Choi PY, Grace RF, Therese Ahlen M, Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Althaus K, Sharma R, Bakchoul T 2021 J Thromb Haemost View Researchers Benchmarking and standard setting
Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity Asamoah-Boaheng M, Goldfarb D, Prusinkiewicz MA, Golding L, Karim ME, Barakauskas V, Wall N, Jassem AN, Marquez AC, MacDonald C, O'Brien SF, Lavoie P, Grunau B 2023 Cureus View Researchers Clinical research
Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates Chi SI, Ramirez-Arcos S 2023 Microorganisms View Researchers Basic research
‘A Most Equitable Drug’: How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development Grundy Q, Campbell C, Ali R, Herder M, Holloway K 2023 J Law Med Ethics View Researchers Ethical, legal & social implications research
Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L, Zhang Z, Kamau PM, Mwangi J, Lu Q, Li Y, Wang Y, MacKeigan DT, Cerenzia EG, Ni H, Lai R 2022 Blood View Researchers Basic research