Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Crosstalk Between Platelets and Microbial Pathogens Li C, Li J, Ni H 2020 Front Immunol View Researchers Basic research
Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LG, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, J.McGeer A, Gommerman JL, Gingras A-C 2020 medRxiv View Researchers Basic research
Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials Kuter DJ, Arnold DM, Rodeghiero F, Janssens A, Selleslag D, Bird R, Newland A, Mayer J, Wang K, Olie R 2020 Am J Hematol View Researchers Clinical research
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W 2021 Adv Ther View Researchers Clinical research
Risk of transfusion-transmitted Babesia microti in Canada O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G 2021 Transfusion View Researchers Benchmarking and standard setting
Effect of modern infusion pumps on RBC quality Hadjesfandiari N, Serrano K, Levin E, Johal P, Feenstra S, Shih AW, Devine DV 2022 Transfusion View Researchers Benchmarking and standard setting
Monocyte monolayer assay predictions of clinical outcome for serologically incompatible red blood cells is all about timing Branch DR, Sandhu G, Raos M 2021 Transfusion View Researchers New or improved product or process
The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia Bissola AL, Daka M, Arnold DM, Smith JW, Moore JC, Clare R, Ivetic N, Kelton JG, Nazy I 2022 Blood Adv View Researchers Clinical research
Understanding the experiences of plasma donors in Canada's new source plasma collection centres during COVID-19: A qualitative study Holloway K 2022 Vox Sang View Researchers Ethical, legal & social implications research
c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance Li F, Xiong Y, Yang M, Chen P, Zhang J, Wang Q, Xu M, Wang Y, He Z, Zhao X, Huang J, Gu X, Zhang L, Sun R, Sun X, Li J, Ou J, Xu T, Huang X, Cao Y, Xu XR, Karakas D, Li J, Ni H, Zhang Q 2022 Cell Death Dis View Researchers Basic research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era Reedman CN, Drews SJ, Yi Q-L, Pambrun C, O’Brien SF 2022 Microbiol Spectr View Researchers Clinical research
A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume Bian Y, Chang TM 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia Ma L, Simpson E, Li J, Xuan M, Xu M, Baker L, Shi Y, Yougbaré I, Wang X, Zhu G, Chen P, Prudhomme GJ, Lazarus AH, Freedman J, Ni H 2015 Blood View Researchers Basic research
Coinfusion of dextrose-containing fluids and red blood cells does not adversely affect in vitro red blood cell quality Keir AK, Hansen AL, Callum J, Jankov RP, Acker JP 2014 Transfusion View Researchers New or improved product or process
c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry McCarthy SDS, Sakac D, Neschadim A, Branch DR 2016 AIDS View Researchers Basic research
Development of antifouling and bactericidal coatings for platelet storage bags using dopamine chemistry Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE 2018 Adv Healthc Mater View Researchers New or improved product or process
Eadie-Hofstee analysis of red blood cell deformability Stadnick H, Onell R, Acker JP, Holovati JL 2011 Clin Hemorheol Microcirc View Researchers Basic research
Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis Marquez-Curtis LA, Janowska-Wieczorek A 2013 BioMed Res Int View Researchers Basic research
From cytokines to pragmatic designs: changing paradigms Heddle NM 2017 Transfusion View Researchers Clinical research
Hope for the Best, but Prepare for the Worst Blake J, Nemergut EC 2014 Anesth Analg View Researchers New or improved product or process
Impact of blood manufacturing and donor characteristics on membrane water permeability and in vitro quality parameters during hypothermic storage of red blood cells Alshalani A, Howell A, Acker JP 2018 Cryobiology View Researchers Basic research
Innate and adaptive immunity in immune thrombocytopenia Lazarus AH, Semple JW, Cines DB 2013 Semin Hematol View Researchers Clinical research
Laboratory management of perinatal patients with apparently "new" anti-D Hannon J, Clarke G 2016 Immunohematology View Researchers Basic research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN 2016 ACS Omega View Researchers Basic research
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A 2016 BMJ Open View Researchers Clinical research
The Platelet as a physiological objection in the circulation Marshall AH, Wang Y, Reheman A, Chen P, Zhu G, Ni H 2014 Pathobiology of human disease: a dynamic encyclopedia of disease mechanisms View Researchers Basic research
Two novel ABCG2 alleles resulting in a Jr (a-) phenotype Berardi P, Cote J, Vege S, Aeschlimann J, Cserti-Gazdewich C, Westhoff CM 2017 Transfusion View Researchers Basic research
MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling Brki J, Dunk C, O'Brien J, Fu G, Nadeem L, Wang Y-l, Rosman D, Salem M, Shynlova O, Yougbare I, Ni H, Lye SJ, Peng C 2018 Mol Ther View Researchers Basic research
Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography Gantioqui J, Stevic I, Atkinson H, Chan AKC 2018 Blood Coagul Fibrinolysis View Researchers Basic research
Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA 2018 J Clin Epidemiol View Researchers Other
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion View Researchers Clinical research
The epidemiology of multicomponent blood transfusion: a systematic review Perelman I, Khair S, Dermer E, Tinmouth A, Saidenberg E, Fergusson D 2019 Transfus Med View Researchers Clinical research
Donneurs de sang total avec anticorps Yan M 2019 Blood.ca website View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
Timeline of heparin-induced thrombocytopenia seroconversion in serial plasma samples tested using an automated latex immunoturbidimetric assay Warkentin TE, Sheppard J-AI, Smith JW, Arnold DM, Nazy I 2019 Int J Lab Hematol View Researchers New or improved product or process
Cluster-randomized trials in transfusion medicine Sirotich E, Barty R, Li N, Arnold DM 2020 Transfusion View Researchers Clinical research
Development of an Ordinal Scale Treatment Endpoint for Adults Hospitalized With Influenza Lee N, Smith SW, Hui DSC, Ye M, Zelyas N, Chan PKS, Drews SJ, Zapernick L, Wong R, Labib M, Shokoples S, Eurich DT 2020 Clin Infect Dis View Researchers Clinical research
Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens AP, Palumbo J, Conway EM, Pryzdial EL, Cullis P, Kastrup CJ 2020 Blood View Researchers Basic research
Current challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed C, Steele W, Davidson K, Custer B, O’Brien S, Assessment ObotSR, Policy sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2021 medRxiv View Researchers Basic research
CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM 2021 J Thromb Haemost View Researchers Basic research
Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada Brennan D, Armstrong JP, Kesler M, Bekele T, Lachowksy N, Grace D, Hart TA, Souleymanov R, Adam B 2023 PLOS Glob Public Health View Researchers MSM research
Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature Germini F, Noronha N, Abraham Philip B, Olasupo O, Pete D, Navarro T, Keepanasseril A, Matino D, de Wit K, Parpia S, Iorio A 2022 J Thromb Haemost View Researchers Clinical research
BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial Ljung R, Chan AKC, Glosli H, Afonja O, Becker B, Tseneklidou-Stoeter D, Mancuso ME, Saulyte-Trakymiene S, Kenet G 2023 Thromb Haemost View Researchers Clinical research
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research
Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles Martinez-Gutierrez F, Thi EP, Silverman JM, de Oliveira CC, Svensson SL, Hoek AV, Sanchez EM, Reiner NE, Gaynor EC, Pryzdial ELG, Conway EM, Orrantia E, Ruiz F, Av-Gay Y, Bach H 2012 Nanomedicine View Researchers Basic research
Blood donor characteristics on transfusion outcomes-should obesity be assessed in future clinical trials?-reply Chasse M, Fergusson DA 2017 JAMA Intern Med View Researchers Clinical research
Chapter 5 - Platelet microRNAs Provost P 2013 Platelets (Third Edition) View Researchers Other
Compatibility of Lactated Ringer's Solution human blood products containing red blood cells: a systematic review protocol Wolfe D, English S, Fergusson D, Kanji S, Lalu M, Mendis N, Tinmouth A, McIntyre L 2016 OHRI Publications View Researchers Clinical research