Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin Branch DR, Scofield TL, Moulds JJ, Swanson JL 2011 Transfusion View Researchers Basic research
Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency Goldman M, Yi Q-L, Steed T, O'Brien SF 2019 Transfusion View Researchers New or improved product or process
Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity Mykhailova O, Olafson C, Turner TR, D?Alessandro A, Acker JP 2020 Transfusion View Researchers Basic research
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H 2022 Transfusion View Researchers Basic research
Implementation of measures to reduce vasovagal reactions: Donor participation and results Goldman M, Uzicanin S, Marquis-Boyle L, O'Brien SF 2021 Transfusion View Health care providers Clinical research
Donor iron policy: from research to practice O'Brien SF 2016 Transfusion View Researchers New or improved product or process
Risks and trends of red blood cell transfusion in obstetric patients: a retrospective study of 45,213 deliveries using administrative data Shehata N, Chassé M, Colas JA, Murphy M, Forster AJ, Malinowski AK, Ducharme R, Fergusson DA, Tinmouth A, Wilson K 2017 Transfusion View Health care providers Clinical research
The Stem Cell Club: a model for unrelated stem cell donor recruitment Fingrut W, Parmar S, Cuperfain A, Rikhraj K, Charman E, Ptak E, Kahlon M, Graham A, Luong S, Wang YG, Yu J, Arora N, Suppiah R, Li EW, Lee A, Welsh C, Benzaquen M, Thatcher A, Baharmand I, Ladd A, Petraszko T, Allan D, Messner H 2017 Transfusion View Health care providers New or improved product or process
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process
Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation Wang A, Singh S, Yu B, Bloch DB, Zapol WM, Kluger R 2019 Transfusion View Researchers Basic research
Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing Taha M, Kyluik-Price D, Kumaran D, Scott MD, Toyofuku W, Ramirez-Arcos S 2019 Transfusion View Researchers Basic research
Could antigen loss be a potential mechanism to explain antibody-mediated immune suppression? Cruz-Leal Y, Lazarus AH 2021 Transfusion View Researchers Basic research
Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada Turner TR, Olafson C, Mykhailova O, Xu A, Acker JP 2020 Transfusion View Researchers New or improved product or process
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion Heddle NM, Cardoso M, van der Meer PF 2020 Transfusion View Researchers Clinical research
Sexual risk behavior questions: Understanding and mitigating donor discomfort Haw J, Woo H, Kohut T, Fisher W 2022 Transfusion View Blood operators MSM research
An evaluation of the clinical impacts of 7-day platelets Ning S, Gabarin N, Li N, Liu Y, Lucier K, Barty R, Acker J, Webert KE, Warkentin TE, Arnold DM, Heddle NM 2023 Transfusion View Researchers Clinical research
Changes in coagulation factor activity and content of di(2-ethylhexyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawing Sheffield WP, Bhakta V, Mastronardi C, Ramirez-Arcos S, Howe D, Jenkins C 2012 Transfusion View Health care providers New or improved product or process
Optimal transfusion practices after allogeneic hematopoietic cell transplantation: a systematic scoping review of evidence from randomized controlled trials Christou G, Iyengar A, Shorr R, Tinmouth A, Saidenberg E, Maze D, Tay J, Bredeson C, Allan DS 2016 Transfusion View Health care providers Clinical research
Selective testing for Trypanosoma cruzi: the first year after implementation at Canadian Blood Services O'Brien SF, Scalia V, Goldman M, Fan W, Yi QL, Dines IR, Huang M, Ndao M, Fearon MA 2012 Transfusion View Blood operators New or improved product or process
Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM 2018 Transfusion View Researchers Clinical research
Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation Turner TR, Lautner L, Hill A, Howell A, Skeate R, Acker JP 2020 Transfusion View Researchers Basic research
Potentially clinically significant anti-Dib identified by monocyte monolayer assay before transfusion Branch DR, Holton MB, Ison T, Cote J, Dube C, Lau W 2021 Transfusion View Researchers Basic research
The utility of a monocyte monolayer assay in the assessment of intravenous immunoglobulin–associated hemolysis Tong TN, Blacquiere M, Sakac D, Burke-Murphy E, Yi Q, Callum J, Cserti-Gazdewich C, Parmar N, Shehata N, Pavenski K, Lau W, Lin Y, Lieberman L, Branch DR, Pendergrast J 2020 Transfusion View Researchers New or improved product or process
Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy Vardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB 2021 Transfusion View Researchers New or improved product or process
Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV 2022 Transfusion View Researchers Basic research
Alternatives to blood donor deferral of gay, bisexual, and other men who have sex with men: Acceptability of screening the sexual risk behavior of all blood donors Fisher WA, Kohut T, Woo H, Haw J 2023 Transfusion View Blood operators MSM research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
Paroxysmal cold hemoglobinuria: a difficult diagnosis in adult patients Zeller MP, Arnold DM, Al Habsi K, Cserti-Gazdewich C, Delage G, Lebrun A, Heddle NM 2017 Transfusion View Health care providers Clinical research
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Ghadaki B, Nazi I, Kelton JG, Arnold DM 2013 Transfusion View Health care providers Clinical research
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
Quality of evidence-based guidelines for platelet transfusion and use: A systematic review Al-Riyami AZ, Jug R, La Rocca U, Keshavarz H, Landry D, Shehata N, Stanworth SJ, Nahirniak S 2021 Transfusion View Researchers Benchmarking and standard setting
How do I think about blood donor eligibility criteria for medical conditions? Goldman M 2021 Transfusion View Researchers Benchmarking and standard setting
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units Pasha R, Elmoazzen H, Pineault N 2017 Transfusion View Researchers New or improved product or process
Exploratory studies on the age of transfused blood and in-hospital mortality in patients with cardiovascular diagnoses Heddle NM, Eikelboom J, Liu Y, Barty R, Cook RJ 2015 Transfusion View Health care providers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Evaluating the appropriateness of platelet transfusions compared with evidence-based platelet guidelines: An audit of platelet transfusions at 57 hospitals Hill-Strathy M, Pinkerton PH, Thompson TA, Wendt A, Collins A, Cohen R, WO BC, Cameron T, Lin Y, Lau W, Lieberman L, Callum J 2021 Transfusion View Health care providers Clinical research
Risk analysis of transfusion of cryoprecipitate without consideration of ABO group Hadjesfandiari N, Levin E, Serrano K, Yi Q-L, Devine DV 2021 Transfusion View Health care providers Benchmarking and standard setting
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM 2022 Transfusion View Researchers Clinical research
Database-driven research and big data analytic approaches in transfusion medicine Ning S, Li N, Barty R, Arnold D, Heddle NM 2022 Transfusion View Researchers Clinical research
2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NLC, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S, for the State of the Science in Transfusion Medicine Working G 2015 Transfusion View Other Other
A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing Acker JP, Hansen AL, Kurach JD, Turner TR, Croteau I, Jenkins C 2014 Transfusion View Blood operators Benchmarking and standard setting
Advancing risk assessment for emerging infectious diseases for blood and blood products: proceedings of a public workshop Gallagher LM, Ganz PR, Yang H, Kessler DA, O'Brien SF, Custer BS, Busch MP, Dodd RY, Stramer SL, Walderhaug MO, Forshee RA, Williams AE, Epstein JS, Anderson SA 2013 Transfusion View Blood operators Other
Changes in plasma unit distributions to hospitals over a 10-year period Seheult JN, Shaz B, Bravo M, Croxon H, Devine D, Doncaster C, Field S, Flanagan P, Germain M, Gregoire Y, Kamel H, Karafin M, Kelting N, Lewis M, O'Brien C, Murphy MF, Rossmann S, Sayers M, Shinar E, Takanashi M, Titlestad K, Yazer MH 2018 Transfusion View Blood operators Clinical research
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC 2010 Transfusion View Researchers Basic research
Impact of platelet transfusion on toxicity and mortality after hematopoietic progenitor cell transplantation Christou G, Kekre N, Petrcich W, Tokessy M, Neurath D, Giulivi A, Saidenberg E, McDiarmid S, Atkins H, Bence-Bruckler I, Bredeson C, Huebsch L, Sabloff M, Sheppard D, Tay J, Tinmouth A, Allan DS 2015 Transfusion View Health care providers Clinical research