Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models Yougbare I, Zdravic D, Ni H 2018 J Pediatr Pediatr Med View Researchers Basic research
In vivo circulation, clearance, and biodistribution of polyglycerol grafted functional red blood cells Chapanian R, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
Neuropeptide Receptors: Novel Targets for HIV/AIDS Therapeutics Branch DR 2011 Pharmaceuticals View Researchers Basic research
Rejuvenation of ATP during storage does not reverse effects of the hypothermic storage lesion Tchir JD, Acker JP, Holovati JL 2013 Transfusion View Researchers Basic research
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
Synthesis and evaluation of linear CuAAC-oligomerized antifreeze neo-glycopeptides van der Wal S, Capicciotti CJ, Rontogianni S, Ben RN, Liskamp RMJ 2014 MedChemComm View Researchers Basic research
The repertoire and features of human platelet microRNAs Ple H, Landry P, Benham A, Coarfa C, Gunaratne PH, Provost P 2012 PLoS One View Researchers Basic research
Whole blood treated with riboflavin and ultraviolet light: quality assessment of all blood components produced by the buffy coat method Schubert P, Culibrk B, Karwal S, Serrano K, Levin E, Bu D, Bhakta V, Sheffield WP, Goodrich RP, Devine DV 2014 Transfusion View Researchers Basic research
Contextual factors influencing donor recruitment and cord blood collection: perspectives of frontline staff of the Canadian Blood Services' Cord Blood Bank Haw J, Polzer J, Devine DV 2019 Transfusion View Researchers New or improved product or process
Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex Kipkeu BJ, Almizraq R, Branch DR, Acker JP, Holovati JL 2018 ISBT Sci Ser View Researchers Basic research
Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment Tseng EK, Jo D, Shih AW, De Wit K, Chan TM 2018 AEM Educ Train View Researchers Education research
Cryoprotection of platelets by grafted polymers Scott M, Nakane N, Maurer-Spurej E 2019 Cryopreservation - Current Advances and Evaluations View Researchers Basic research
Monitoring of prenatal patients using a combined antibody titre for Rh and non-Rh antibodies Farrell M, Clarke G, Barr G, Hannon J 2020 Transfus Med View Researchers Clinical research
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-?TP-L309C, a recombinant IgG1 Fc hexamer Lewis BJB, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher AW, Käsermann F, Branch DR 2019 BMC Immunol View Researchers Basic research
Concentré de recherche: L’apprentissage automatique pour mieux évaluer la qualité des globules rouges Acker JP 2020 Blood.ca website Researchers Basic research
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP 2021 Transfusion View Researchers New or improved product or process
Multicenter observational study evaluating the impact of platelet transport bags on product wastage Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J 2021 Transfusion View Researchers New or improved product or process
Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin Khan H, Gallant R, Jain S, Al-Omran M, De Mestral C, Greco E, Wheatcroft M, Alazonni A, Abdin R, Rand ML, Ni H, Qadura M 2020 Medicina View Researchers Clinical research
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P 2021 Res Pract Thromb Haemost View Researchers Clinical research
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A 2021 Transfusion View Researchers Clinical research
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I 2021 Nature View Researchers Clinical research
User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study Germini F, Borg Debono V, Page D, Zuk V, Kucher A, Cotoi C, Hobson N, Sevestre M, Skinner MW, Iorio A 2022 JMIR Hum Factors View Researchers Benchmarking and standard setting
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW 2021 Blood Coagul Fibrinolysis View Researchers Clinical research
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial Bartoszko J, Callum J, Karkouti K 2021 Can J Anaesth View Researchers Clinical research
A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates Chelle P, Iorio A, Edginton AN 2022 J Thromb Haemost View Researchers Basic research
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals Grunau B, Prusinkiewicz M, Asamoah-Boaheng M, Golding L, Lavoie PM, Petric M, Levett PN, Haig S, Barakauskas V, Karim ME, Jassem AN, Drews SJ, Sediqi S, Goldfarb DM 2022 Microbiol Spectr View Researchers Clinical research
Frequency and utility of bone marrow examination in relapsed/refractory immune thrombocytopenia Taparia K, Wall E, Arnold DM, Sun HL 2022 J Thromb Haemost View Researchers Clinical research
ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes Wolofsky KT, Ayi K, Branch DR, Hult AK, Olsson ML, Liles WC, Cserti-Gazdewich CM, Kain KC 2012 PLoS Pathog View Researchers Basic research
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA Kalathottukaren MT, Abraham L, Kapopara PR, Lai BFL, Shenoi RA, Rosell FI, Conway EM, Pryzdial ELG, Morrissey JH, Haynes CA, Kizhakkedathu JN 2016 Blood View Researchers Basic research
Can natural antibodies to VIP or VIP-like HIV-1 glycoprotein facilitate prevention and supportive treatment of breast cancer? Veljkovic M, Branch DR, Dopsaj V, Veljkovic V, Veljkovic N, Glisic S, Colombatti A 2011 Med Hypotheses View Researchers Basic research
Concentré de recherche: Mais où va le sang? Analysons la consommation des concentrés de globules rouges pour l'établissement des politiques Zeller M, Heddle N, Devine D 2017 Blood.ca website View Researchers Basic research
Detection of bacterial adherence and biofilm formation on medical surfaces Loza-Correa M, Ramirez-Arcos S 2016 Biofilms and implantable medical devices: infection and control View Researchers New or improved product or process
Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury Kapur R, Kim M, Rondina MT, Porcelijn L, Semple JW 2016 Oncotarget View Researchers Basic research
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ 2017 Pediatr Crit Care Med View Researchers Clinical research
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD 2015 Am J Hematol View Researchers Basic research
Label-free assessment of red blood cell storage lesions by deep learning Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE 2018 bioRxiv View Researchers New or improved product or process
Mechanisms of platelet recovery in ITP associated with therapy Pang SJY, Lazarus AH 2010 Ann Hematol View Researchers Basic research
Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype Berardi P, Cote J, Clarke G, Scalia V, Liwski R, Goldman M 2017 Transfusion View Researchers New or improved product or process
Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration Branch DR 2011 Future Virol View Researchers Basic research
Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease Kanias T, Sinchar D, Osei-Hwedieh D, Baust JJ, Jordan A, Zimring JC, Waterman HR, de Wolski KS, Acker JP, Gladwin MT 2016 Transfusion View Researchers Basic research
Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use Lin Y, Cohen R, Armali C, Callum J, Cserti-Gazdewich C, Lieberman L, Pendergrast J 2018 Vox Sang View Researchers Clinical research
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA 2018 Blood Adv View Researchers Basic research
Microvascular Thrombosis and Ischaemic Limb Losses in Critically Ill Patients Warkentin TE 2019 Hämostaseologie View Researchers Clinical research
Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment Jahan S, Adam MK, Manesia JK, Doxtator E, Ben RN, Pineault N 2020 Transfusion View Researchers Basic research
Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor Nazy I, Elliott TD, Arnold DM 2020 Br J Haematol View Researchers Basic research
A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium Drews SJ, Lesley P, Detsky ME, Distefano L, Ilagan C, Mehta S, McGeer A, Shehata N, Skeate R, Ramirez-Arcos S 2020 Transfusion View Researchers Basic research
Evaluation of the effect of T regulatory cell depletion and donor BCG vaccination on Mycobacterium tuberculosis H37Ra infection using an in vitro model of human PBMC infection Bhavanam S, Rayat GR, Keelan M, Kunimoto D, Drews SJ 2020 Pathog Dis View Researchers Basic research
Insights Into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics Hovey O, Pasha R, Lehmann Z, Pineault N 2020 Proteomics View Researchers Basic research
The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia Huynh A, Arnold DM, Smith JW, Elliott TD, Ivetic N, Kelton JG, Nazy I 2020 Thromb Res View Researchers Basic research