Research

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Our Funded Research Projects

Updated November 2017

Displaying 51 - 100 of 108.
E.g., 2017-12-10
E.g., 2017-12-10
Project Investigator(s) Program Start Date End Date Total $ Awarded
Pre-transfusion furosemide for TACO Principal Investigator:
SKEATE, Robert
Canadian Blood Services

Co-Investigator(s) / Trainee:
CALLUM, Jeannie
Small Project Funding Program Sep 1, 2016 Aug 31, 2017 $15,000
ROTEM-guided transfusion protocols - impact on the manufacturer Principal Investigator:
TRUDEAU, Jacqueline
University of British Columbia

Co-Investigator(s) / Trainee:
PETRASZKO, Tanya
LI, Cecilia
Small Project Funding Program Sep 1, 2016 Aug 31, 2017 $15,000
National evaluation of platelet transport bags to reduce wastage Principal Investigator:
WEBERT, Kathryn
Canadian Blood Services

Co-Investigator(s) / Trainee:
CALLUM, Jeannie
LIN, Yulia
LIEBERMAN, Lani
PENDERGRAST, Jacob
CSERTI-GAZDEWICH, Christine
Small Project Funding Program Jul 1, 2016 Jun 30, 2017 $9,740
Use of red blood cell antigen genotyping to assess RhD diversity in sickle cell disease patients Principal Investigator:
SHIH, Andrew
McMaster University

Co-Investigator(s) / Trainee:
BERARDI, Philip
CLARKE, Gwen
HANNON, Judith
HEDDLE, Nancy
VERHOVSEK, Madeleine
Small Project Funding Program Jul 1, 2016 Jun 30, 2017 $15,000
Neonatal outcomes after transfusion of ABO non-identical blood (Neo-ABO) Principal Investigator:
SOLH, Ziad
McMaster University

Co-Investigator(s) / Trainee:
HEDDLE, Nancy
COOK, Richard J.
FUSCH, Christoph
Small Project Funding Program Sep 1, 2016 Aug 31, 2017 $14,989
Data sharing with CBMTG registry Principal Investigator:
ALLAN, David
The Ottawa Hospital

Co-Investigator(s) / Trainee:
PAULSON, Kristjan
Small Project Funding Program Dec 1, 2016 Nov 30, 2017 $15,000
The Stem Cell Club: educating medical and nursing students to develop professional skills Principal Investigator:
FINGRUT, Warren
University of Toronto
BloodTechNet Award Program Jun 1, 2016 May 31, 2017 $24,458
Social media for knowledge translation and education 3 (SoMe-KTE3): Transfusion, thrombosis, and hemostasis Principal Investigator:
SHIH, Andrew
McMaster University

Co-Investigator(s) / Trainee:
CHAN, Teresa
DE WIT, Kristin
BHAGIRATH, Vinai
YEH, Calvin
CASTELLUCI, Lana
ELAHIE, Allahna
HEDDLE, Nancy
THOMA, Brent
BloodTechNet Award Program Jun 1, 2016 May 31, 2018 $30,000
The use of antibody-mediated immune suppression as a model in the development of a replacement for RhD prophylaxis in haemolytic disease of the fetus and newborn Principal Investigator:
LAZARUS, Alan
St. Michael's Hospital
Canadian Blood Services-CIHR Partnership Operating Grant Program Mar 1, 2011 Feb 20, 2017 $620,822
Small molecule inhibitors of phagocytosis as replacement therapy for IVIG Principal Investigator:
BRANCH, Donald
St. Michael's Hospital

Co-Investigator(s) / Trainee:
KOTRA, Lakshmi, P.
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2013 Mar 31, 2016 $409,127
Development of novel blood vessel and organ sealants for blood conservation in surgical practice Principal Investigator:
BROOKS, Don
University of British Columbia

Co-Investigator(s) / Trainee:
DU, Caigan
HSIANG, York N.
KIZHAKKEDATHU, Jayachandran N.
KO, Frank K.
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2013 Mar 31, 2017 $240,996
Platelet microRNAs during storage under blood bank conditions Principal Investigator:
PROVOST, Patrick
University of Laval

Co-Investigator(s) / Trainee:
HITZLER, Walter
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2013 Sep 30, 2016 $349,548
Transfusion-related Epstein-Barr Virus (EBV) infection among allogeneic stem cell transplant pediatric recipients: A multicenter prospective cohort study (TREASuRE Study) Principal Investigator:
TROTTIER, Helen
Hopital Sainte-Justine

Co-Investigator(s) / Trainee:
ALFIERI, Carolina
BUTEAU, Chantal
DUVAL, Michel
LACROIX, Jacques
ROBITAILLE, Nancy
SPINELLA, Philip
TUCCI, Marisa
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2013 Jun 30, 2017 $519,766
Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing major liver resection: a pilot randomized controlled trial Principal Investigator:
KARANICOLAS, Paul
Sunnybrook Research Institute

Co-Investigator(s) / Trainee:
GUYATT, Gordon H.
CHAUDHURY, Prosanto K.
DIXON, Elijah
LIN, Yulia
McCLUSKEY, Stuart A.
PORTER, Geoffrey A.
TARSHIS, Jordan
WEI, Alice C.
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2014 Mar 31, 2017 $248,319
Understanding host mechanisms responsible for immune platelet destruction and thrombocytopenia Principal Investigator:
SEMPLE, John
St. Michael's Hospital
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2014 Mar 31, 2017 $406,003
Polyhemoglobin catalase superoxide dismutase carbonic anhydrase: a novel soluble biotherapeutic with no cardiac toxicity for hemorrhagic shock and other uses Principal Investigator:
CHANG, Thomas
McGill University
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2014 Mar 31, 2018 $224,520
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator:
PINEAULT, Nicolas
Canadian Blood Services

Co-Investigator(s) / Trainee:
CAMPBELL, Pearl
GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2014 Mar 31, 2018 $320,504
Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking Principal Investigator:
KLUGER, Ronald
University of Toronto
Canadian Blood Services-CIHR Partnership Operating Grant Program Apr 1, 2014 Sep 30, 2017 $192,039
Release, delivery and cell programming effects of platelet microparticles and microRNAs Principal Investigator:
PROVOST, Patrick
University of Laval

Co-Investigator(s) / Trainee:
BOILARD, Eric
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Mar 31, 2018 $427,422
Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease Principal Investigator:
TRUDEL, Marie
Institut de recherches cliniques do Montreal

Co-Investigator(s) / Trainee:
MOROY, Tarik
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Sep 30, 2017 $453,132
Pathogenesis and treatment of immune thrombocytopenia: Are there fundamental differences between anti-GPlba- and anti-GPllbllla-mediated thrombocytopenia? Principal Investigator:
NI, Heyu
St. Michael's Hospital
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Sep 30, 2017 $378,529
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) Principal Investigator:
KUEBLER, Wolfgang
St. Michael's Hospital

Co-Investigator(s) / Trainee:
SEMPLE, John W.
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Sep 30, 2017 $328,712
Short and long-term clinical effects of blood donor characteristics in transfusion recipients Principal Investigator:
FERGUSSON, Dean
Ottawa Hospital Research Institute

Co-Investigator(s) / Trainee:
ACKER, Jason P.
CHASSÉ, Michael
ENGLISH, Shane
FORSTER, Alan
KNOLL, Greg
McINTYRE, Lauralyn A.
SHEHATA, Nadine
van WALRAVEN, Carl
WILSON, Kumanan
TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Sep 30, 2016 $103,806
Exploratory analyses to determine if method of donor blood processing affects outcome in transfused recipients Principal Investigator:
HEDDLE, Nancy
McMaster University

Co-Investigator(s) / Trainee:
ACKER, Jason P.
ARNOLD, Donald M.
COOK, Richard J.
EIKELBOOM, John W.
O'BRIEN, Sheila F.
WEBERT, Kathryn E.
Canadian Blood Services-CIHR Partnership Operating Grant Program Oct 1, 2014 Jun 30, 2017 $159,878
Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study Principal Investigator:
TINMOUTH, Alan
Ottawa Hospital Research Institute

Co-Investigator(s) / Trainee:
CHASSÉ, Michael
FERGUSSON, Dean A.
GOLDMAN, Mindy R.
O'BRIEN, Sheila F.
SPRAGUE, Ann
van WALRAVEN, Carl
WALKER, Mark C
WILSON, Kumanan
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Mar 31, 2018 $135,657
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) Principal Investigator:
SEMPLE, John
St. Michael's Hospital

Co-Investigator(s) / Trainee:
KUEBLER, Wolfgang M.
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $398,982
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator:
EMERIAUD, Guillaume
Hopital Sainte-Justine

Co-Investigator(s) / Trainee:
Du PONT-THIBIDEAU, Genevieve
FONTELA, Patricia S.
GAUVIN, France
GILFOYLE, Elaine
HUTCHISON, James S.
LACROIX, Jacques
MENON, Kusum
ROBITAILLE, Nancy
TINMOUTH, Alan T.
TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $477,651
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator:
ARNOLD, Donald
McMaster University

Co-Investigator(s) / Trainee:
COOK, Richard J.
NAZI, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $317,469
Polymer-based manufacturing tolerogenic miRNA-based therapeutics Principal Investigator:
SCOTT, Mark
Canadian Blood Services

Co-Investigator(s) / Trainee:
HORWITZ, Marc S.
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $491,125
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator:
ENGLISH, Shane
Ottawa Hospital Research Institute

Co-Investigator(s) / Trainee:
McINTYRE, Lauralyn A.
ALGIRD, Almunder
BOUTIN, Amélie
CHASSE, Michael
DOWLATSHAHI, Dariush
FERGUSSON, Dean A.
GRIESDALE, Donald
KRAMER, Andreas H.
LAUZIER, François
LUM, Cheemun
MARSHALL, Shawn C.
PAGLIARELLO, Giuseppe
SINCLAIR, John
TINMOUTH, Alan T.
TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $157,172
Myocardial Ischemia and Transfusion. The MINT rollover trial Principal Investigator:
HEBERT, Paul
Centre Hospitalier de l'Universite de Montreal

Co-Investigator(s) / Trainee:
CARSON, Jeffrey L.
DEVEREAUX, Philip J.
EIKELBOOM, John W.
FERGUSSON, Dean A.
GOODMAN, Shaun G.
MCALISTER, Finlay A.
TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2015 Jun 30, 2018 $140,210
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator:
NI, Heyu
St. Michael's Hospital
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2017 Jun 30, 2020 $447,525
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator:
NI, Heyu
St. Michael's Hospital
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2017 Jun 30, 2020 $378,675
Expanding treatment options for inflammatory bowel disease: a novel mechanism of antibody-based immunotherapy Principal Investigator:
SLY, Laura
University of British Columbia

Co-Investigator(s) / Trainee:
HORWITZ, Marc
BRESSLER, Brian
RASSEKH, Rod
TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program Jul 1, 2017 Jun 30, 2020 $387,855
Elucidation of the cechanism of IVIG-associated hemolysis Principal Investigator:
BRANCH, Donald
Canadian Blood Services

Co-Investigator(s) / Trainee:
PENDERGRAST, Jacob
CSERTI-GAZDEWICH, Christine
SHEHATA, Nadine
PAVENSKI, Katerina
LAU, Wendy
CALLUM, Jeannie
LIN, Yulia
LIEBERMAN, Lani
HANNACH, Barbara
Intramural Research Grant Program Oct 1, 2014 Oct 31, 2017 $393,712
Defining the components of transfusable plasma that reduce bleeding Principal Investigator:
SHEFFIELD, William
McMaster University

Co-Investigator(s) / Trainee:
PRYZDIAL, Edward
NI, Heyu
Intramural Research Grant Program Nov 1, 2014 Feb 28, 2017 $218,230
Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) Principal Investigator:
LAZARUS, Alan
St. Michael's Hospital

Co-Investigator(s) / Trainee:
SEMPLE, John W.
NI, Heyu
Intramural Research Grant Program Nov 1, 2015 Oct 31, 2018 $400,000
Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation Principal Investigator:
ACKER, Jason P
University of Alberta

Co-Investigator(s) / Trainee:
HOLOVATI, Jelena
BRANCH, Donald
ZHANG, Haibo
Intramural Research Grant Program Nov 1, 2015 Sep 30, 2018 $250,660
Human monoclonal CD44 antibodies as potential IVIg replacements Principal Investigator:
LAZARUS, Alan
St. Michael's Hospital

Co-Investigator(s) / Trainee:
NI, Heyu
Intramural Research Grant Program Oct 1, 2016 Sep 30, 2018 $336,000
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator:
SHEFFIELD, William
McMaster University

Co-Investigator(s) / Trainee:
NI, Heyu
Intramural Research Grant Program Oct 31, 2016 Oct 30, 2018 $224,417
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator:
WEBERT, Kathryn
McMaster University

Co-Investigator(s) / Trainee:
NAHIRNIAK, Susan
CALLUM, Jeannie
LIN, Yulia
ZELLER, Michelle
Intramural Research Grant Program Dec 1, 2016 Nov 30, 2018 $332,942
Legal and policy strategies to optimize organ donation in Alberta Principal Investigator:
TOEWS, Maeghan
University of Alberta
James Kreppner Fellowship Program Oct 1, 2014 Sep 30, 2016 $150,000
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator:
GRUBEN, Vanessa
University of Ottawa
James Kreppner Fellowship Program Nov 1, 2015 Oct 31, 2017 $150,000
Prospective observational study of organ deceased donor management in 3 ICUs - a pilot study (the DONATE pilot study) Principal Investigator:
MEADE, Maureen
McMaster University

Co-Investigator(s) / Trainee:
D'ARAGON, Frederick
Kenneth J. Fyke Award Program Mar 1, 2015 Jun 30, 2017 $89,555
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator:
ALLAN, David
Ottawa Hospital Research Institute

Co-Investigator(s) / Trainee:
HUTTON, Brian
CAULFIELD, Timothy
Kenneth J. Fyke Award Program Jul 1, 2017 Jun 30, 2018 $100,000
The role of stakeholder trust in OTDT policy change: public and professional attitudes to ante-mortem interventions in organ donation Principal Investigator:
CHANDLER, Jennifer
University of Ottawa

Co-Investigator(s) / Trainee:
McKAY, Lindsey
James Kreppner Fellowship Program Oct 1, 2017 Sep 30, 2018 $50,000
Pathogenesis of fetal and neonatal alloimmune thrombocytopenia and mechanisms of IVIG therapy Principal Investigator:
NI, Heyu
St. Michael's Hospital

Co-Investigator(s) / Trainee:
YOUGBARE, Issaka
Postdoctoral Fellowship Program Oct 1, 2012 Sep 30, 2016 $151,800
Mechanism of anti-D-like antibody-mediated amelioration of immune thrombocytopenia (ITP) Principal Investigator:
LAZARUS, Alan
St. Michael's Hospital

Co-Investigator(s) / Trainee:
YU, Xiaojie (Ben)
Postdoctoral Fellowship Program Nov 3, 2014 May 11, 2016 $106,200
Transfusion options in coagulopathy: efficacy in controlling bleeding Principal Investigator:
SHEFFIELD, William
McMaster University

Co-Investigator(s) / Trainee:
QADRI, Syed
Postdoctoral Fellowship Program Jan 2, 2015 Jan 1, 2018 $151,800
Understanding IVIg mechanism(s) of action in alleviating immune platelet destruction and thrombocytopenia Principal Investigator:
SEMPLE, John
University of Toronto

Co-Investigator(s) / Trainee:
KAPUR, Ricky
Postdoctoral Fellowship Program Jan 12, 2015 Jan 11, 2017 $106,200