Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures van der Meer PF, Cancelas JA, Cardigan R, Devine DV, Gulliksson H, Sparrow RL, Vassallo RR, de Wildt-Eggen J, Baumann-Baretti B, Hess JR, for the BC 2011 Transfusion View Blood operators New or improved product or process
In vitro platelet quality in storage containers used for pediatric transfusions Weiss S, Scammell K, Levin E, Culibrk B, Zolfaghari S, Gyongyossy-Issa MI, Acker JP 2012 Transfusion View Health care providers New or improved product or process
Iron deficiency in Canadian blood donors Goldman M, Uzicanin S, Scalia V, O'Brien SF 2014 Transfusion View Health care providers Clinical research
Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP 2017 Transfusion View Researchers Basic research
Platelet concentrates from fresh or overnight-stored blood, an international study Dijkstra-Tiekstra MJ, van der Meer PF, Cardigan R, Devine D, Prowse C, Sandgren P, de Wildt-Eggen J, for the Biomedical Excellence for Safer Transfusion C 2011 Transfusion View Blood operators New or improved product or process
Closing in on DEHP-free red blood cell concentrate containers Almizraq RJ, Acker J 2018 Transfusion View Researchers New or improved product or process
Educating the next frontier of transfusionists: a transfusion camp pilot program for nurse practitioners Shih AW, Morrison D, Sekhon AS, Lin Y, Charge S, Chipperfield K, Beaveridge J 2020 Transfusion View Health care providers Other
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H 2021 Transfusion View Researchers New or improved product or process
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M 2021 Transfusion View Researchers Basic research
Implementation of a blood bank generated tube for second blood group determination: Challenges, yield, and cost Obaidallah N, Downie H, Colavecchia C, Callum J, Lin Y 2022 Transfusion View Health care providers New or improved product or process
A new tool to assess bleeding severity in patients with chemotherapy-induced thrombocytopenia (CME) Webert KE, Arnold DM, Lui Y, Carruthers J, Arnold E, Heddle NM 2012 Transfusion View Health care providers Clinical research
Acute hemolysis after intravenous immunoglobulin amid host factors of ABO-mismatched bone marrow transplantation, inflammation, and activated mononuclear phagocytes Michelis FV, Branch DR, Scovell I, Bloch E, Pendergrast J, Lipton JH, Cserti-Gazdewich CM 2014 Transfusion View Health care providers Clinical research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
CD44 antibody-mediated amelioration of murine immune thrombocytopenia (ITP): mouse background determines the effect of FcgammaRIIb genetic disruption Crow AR, Amash A, Lazarus AH 2014 Transfusion View Researchers Basic research
Coagulation factor content of plasma produced from whole blood stored for 24 hours at ambient temperature: results from an international multicenter BEST Collaborative study Cardigan R, Van der Meer PF, Pergande C, Cookson P, Baumann-Baretti B, Cancelas JA, Devine D, Gulliksson H, Vassallo R, de Wildt-Eggen J 2011 Transfusion View Blood operators New or improved product or process
Cryopreservation of adult unrelated donor products in hematopoietic cell transplantation: the OneMatch experience and systematic review of the literature Aziz J, Morris G, Rizk M, Shorr R, Mercer D, Young K, Allan D 2017 Transfusion View Researchers Clinical research
Development of a proof of principle for universal neutralization of antibiotics in cord blood by-products used for sterility testing Kou Y, Halpenny M, Elmoazzen H, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Impact of a 5-year deferral from blood donation for men who have sex with men O'Brien SF, Osmond L, Fan W, Yi Q-L, Goldman M 2015 Transfusion View Blood operators Benchmarking and standard setting
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
Supernatant reduction of stored gamma?irradiated red blood cells minimizes potentially harmful substances present in transfusion aliquots for neonates Serrano K, Pambrun C, Levin E, Devine DV 2017 Transfusion View Health care providers New or improved product or process
Triplets with neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1a Solh Z, Breakey V, Murthy P, Smith JW, Arnold DM 2016 Transfusion View Health care providers Clinical research
Immunotherapy: the good, the bad, the ugly, and the really ugly Branch DR 2019 Transfusion View Researchers Clinical research
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 Atreya C, Glynn S, Busch M, Kleinman S, Snyder E, Rutter S, AuBuchon J, Flegel W, Reeve D, Devine D, Cohn C, Custer B, Goodrich R, Benjamin RJ, Razatos A, Cancelas J, Wagner S, Maclean M, Gelderman M, Cap A, Ness P 2019 Transfusion View Researchers New or improved product or process
Blood donation and testosterone replacement therapy Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I 2017 Transfusion View Health care providers Clinical research
Changing trends in blood transfusion: an analysis of 244,013 hospitalizations Shehata N, Forster A, Lawrence N, Rothwell DM, Fergusson D, Tinmouth A, Wilson K 2014 Transfusion View Health care providers Clinical research
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J 2017 Cell Rep View Researchers Basic research
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory Yudin J, Heddle NM 2014 Lab Med View Health care providers Clinical research
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP 2023 Sci Rep View Researchers Basic research
IVIG regulates the survival of human but not mouse neutrophils Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S 2017 Sci Rep View Researchers Basic research
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP 2017 Sci Rep View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H 2017 Sci Rep View Researchers New or improved product or process
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR 2011 Viral Immunol View Researchers Basic research
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG 2015 Eur J Haematol View Researchers Clinical research
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM 2013 Eur J Haematol View Health care providers Clinical research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B 2019 Eur J Haematol View Researchers Clinical research
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N 2017 Eur J Haematol View Researchers Basic research