Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T 2021 Blood View Researchers Basic research
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC 2021 Front Genet View Researchers Basic research
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP 2021 Transfusion View Researchers New or improved product or process
Multicenter observational study evaluating the impact of platelet transport bags on product wastage Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J 2021 Transfusion View Researchers New or improved product or process
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P 2021 Res Pract Thromb Haemost View Researchers Clinical research
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A 2021 Transfusion View Researchers Clinical research
Research Unit: A more accurate and efficient way to manage blood demand and supply Li N 2021 Blood.ca website View Health care providers New or improved product or process
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I 2021 Nature View Researchers Clinical research
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW 2021 Blood Coagul Fibrinolysis View Researchers Clinical research
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial Bartoszko J, Callum J, Karkouti K 2021 Can J Anaesth View Researchers Clinical research
Administration de produits sanguins O'Reilly C 2021 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
The Monocyte Monolayer Assay to Build a Personalized Pipeline of Transfusion Support in Highly Sensitized Sickle Cell Disease Vijenthira S, Nguyen J, Branch DR, Clarke G, Ward R, Saeed S, Cserti-Gazdewich C 2021 Blood View Health care providers New or improved product or process
Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis Sklavounos AA, Lamanna J, Modi D, Gupta S, Mariakakis A, Callum J, Wheeler AR 2021 Clin Chem View Researchers New or improved product or process
The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada O’Brien SF, Lewin A, Yi Q-L, Dowling G, Fissette E, Drews SJ 2021 Cell Tissue Bank View Health care providers Clinical research
Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion Ebraheem MS, Verhovsek M 2021 Blood Adv View Health care providers Clinical research
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N 2021 Vox Sang View Researchers Clinical research
Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances McVey MJ, Cohen R, Arsenault V, Escorcia A, Tasmin F, Pendergrast J, Lieberman L, Lin Y, Callum J, Cserti-Gazdewich C 2021 Vox Sang View Health care providers Clinical research
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant Hamada M, Bhakta V, Andres SN, Sheffield WP 2021 Front Cardiovasc Med View Researchers Basic research
International Forum on Walking Blood Bank Programmes: Responses Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N 2021 Vox Sang View Blood operators New or improved product or process
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T 2021 Blood View Researchers Clinical research
Buffy coat platelets coming to America: Are we ready? Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R 2021 Transfusion View Blood operators New or improved product or process
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B 2021 Intensive Care Med Researchers Clinical research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion Leatherdale A, Parker DA, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM 2021 J Thromb Haemost View Researchers Basic research
Research initiatives of blood services worldwide in response to the covid-19 pandemic O'Brien SF, Lieshout-Krikke RW, Lewin A, Erikstrup C, Steele WR, Uzicanin S, Custer B, the Surveillance RA, Policy Sub-group of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2021 Vox Sang View Researchers Clinical research
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins CC, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates SM, Lang E, Le Gal G, Haramati LB, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa RA 2021 Blood Adv View Researchers Clinical research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I 2021 Viruses View Researchers Clinical research
An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study Germain M, Grégoire Y, Custer BS, Goldman M, Bravo M, Kamel H, Davison K, Field S, van den Hurk K, van de Laar TJW, Irving DO, Jones A, Liumbruno G, Morley S, O’Brien SF, Pillonel J, Steinsvåg CT, Takanashi M, Tsuno NH, Vesga Carasa MA, Wendel S, Vassallo RR, Tiberghien P, for the BEST Collaborative 2021 Vox Sang View Researchers Benchmarking and standard setting
Concentré de recherche: L’administration d’albumine par voie intraveineuse ne conduit pas à de meilleurs résultats chez les personnes subissant des opérations cardiaques Bartoszko J 2021 Blood.ca website View Health care providers Clinical research
International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Responses Goldman M, Townsend M, Magnussen K, Lozano M, Nissen-Meyer LSH, Lee CK, Leung JN, Takanashi M, McKay J, Kvist M, Robitaille N, Deschênes J, Di Angelantonio E, McMahon A, Roberts D, Maghsudlu M, Castrén J, Tiberghien P, Woimant G, Morel P, Kamel H, Bravo M, Shinar E, Gendelman V, Raz H, Wendel S, Fachini R, Quee F, van den Hurk K, Wiersum J, Grima KM, Speedy J, Bruun MT, Dunbar NM 2021 Vox Sang View Health care providers Benchmarking and standard setting
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W 2021 Adv Ther View Researchers Clinical research
Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology Sirotich E, Guyatt G, Gabe C, Ye Z, Beck CE, Breakey V, Cooper N, Cuker A, Charness J, de Wit K, DiRaimo J, Fein SG, Grace RF, Hassan Z, Jamula E, Kang M, Manski CF, O'Connor C, Pai M, Paynter D, Porter SC, Pruitt B, Strachan G, Webert KE, Yan JW, Kelton JG, Bakchoul T, Arnold DM 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
Risk of transfusion-transmitted Babesia microti in Canada O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G 2021 Transfusion View Researchers Benchmarking and standard setting
Réactions transfusionnelles anaphylactiques et déficit en IgA Khandelwal A, Clarke G, Goldman M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Factors associated with wrong blood in tube errors: An international case series - The BEST collaborative study Dunbar NM, Kaufman RM 2021 Transfusion View Health care providers Benchmarking and standard setting
Monocyte monolayer assay predictions of clinical outcome for serologically incompatible red blood cells is all about timing Branch DR, Sandhu G, Raos M 2021 Transfusion View Researchers New or improved product or process
Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic Wendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P, Lee C-K, Arora S, Patidar GK, Khillan K, Smid WM, Vrielink H, Oreh A, Al-Riyami AZ, Hindawi S, Vermeulen M, Louw V, Burnouf T, Bloch EM, Goel R, Townsend M, So-Osman C 2021 Vox Sang View Blood operators New or improved product or process
Chapter 11: Massive hemorrhage and emergency transfusion Trudeau J, Dawe P, Shih A 2021 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Current challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed C, Steele W, Davidson K, Custer B, O’Brien S, Assessment ObotSR, Policy sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2021 medRxiv View Researchers Basic research
International Forum on Walking Blood Bank Programmes: Summary Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Sekaran Nadarajan V, Dunbar N 2021 Vox Sang View Blood operators Benchmarking and standard setting
CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM 2021 J Thromb Haemost View Researchers Basic research
Rethinking platelet transfusion practices Devine DV 2021 Blood View Health care providers New or improved product or process
Convalescent plasma for hospitalized patients with COVID-19 and the effect of plasma antibodies: a randomized controlled, open-label trial Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A, Arnold DM, for The CONCOR-1 Study Group 2021 medRxiv View Health care providers Clinical research
Necrotizing enterocolitis and mortality after transfusion of ABO non-identical blood Parvizian MK, Barty R, Heddle NM, Li N, McDougall T, Mukerji A, Fusch C, Solh Z 2021 Transfusion View Researchers Clinical research
Mechanism of increased efficacy of recombinant Fc-?TP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR 2021 eJHaem View Researchers Basic research
Evidence of SARS-CoV-2 Infection in Cells, Tissues, and Organs and the Risk of Transmission Through Transplantation Gaussen A, Hornby L, Rockl G, O’Brien S, Delage G, Sapir-Pichhadze R, Drews SJ, Weiss MJ, Lewin A 2021 Transplantation View Health care providers Clinical research
The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters Choi PY, Grace RF, Therese Ahlen M, Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Althaus K, Sharma R, Bakchoul T 2021 J Thromb Haemost View Researchers Benchmarking and standard setting
ResearchUnit: Intravenous albumin is not associated with improved outcomes in cardiac surgery patients Bartoszko J 2021 Blood.ca website View Health care providers Clinical research