Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Project Start Date Sort ascending Project End Date Total $ Awarded
Hypothermic Storage as an Alternative to Irradiation of Red Cell Concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: CLARKE, Gwen, NAHIRNIAK, Susan, BRANDON-COATHAM, Mackenzie, OLAFSON, Carly
Blood Efficiency Accelerator Program 30000.0
Red Cell Transfusion Rate and Allosensitization in Patients with End Stage Kidney Disease Principal Investigator: ZIMMERMAN, Deborah

Co-Investigator(s) / Trainee: FERGUSSON, Dean, FORSTER, Alan, KNOLL, Greg, CALLUM, Jeannie, TINMOUTH, Alan, MACK, Johnathan, CLARK, Edward, RAMSAY, Tim, PERELMAN, Iris
Blood Efficiency Accelerator Program 29015.7
A Simulation Model to Inform Best Practices for Inventory Management of Group O Negative Red Blood Cells Principal Investigator: RUTHERFORD, Alexander

Co-Investigator(s) / Trainee: BLAKE, John, SHIH, Andrew, MORRISON, Douglas, SAREMI, Alireza
Blood Efficiency Accelerator Program 29500.0
Rationale, development, and feasibility of a prehospital transfusion registry Principal Investigator: NOLAN, Brodie

Co-Investigator(s) / Trainee: PEDDLE, Michael, LIN, Yulia, KHANDELWAL, Aditi, MCGOWAN, Melissa, TROJANOWSKI, Jan, SHIH, Andrew
Blood Efficiency Accelerator Program 30000.0
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program 50000.0
Study of Whole Blood In Frontline Trauma-2 (SWIFT-2) Principal Investigator: BECKETT, Andrew

Co-Investigator(s) / Trainee: SINGH, Kanwal
Postdoctoral Fellowship Program 20500.0
Clot-targeting the novel thrombolytic activity of recombinant factor X Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: HAO, Lihua
Postdoctoral Fellowship Program 164200.0
Evaluating transfusion medicine patterns of practice across GEMINI sites Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse
Kenneth J. Fyke Award Program 98822.0
Replacing plasma-derived C1 Esterase inhibitor Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: SIVANANTHAN, Sangavi
Graduate Fellowship Program 70000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ROTIN, Lianne
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: RAZA, Sheharyar
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ARYA, Sumedha
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: LI, Wenhui
Graduate Fellowship Program 70000.0
Developing educational tools and resources to improve living donor care Principal Investigator: SANDAL, Shaifali

Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather
BloodTechNet Award Program 50000.0
Anemia-induced bleeding in thrombocytopenic patients with blood cancer Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: MODI, Dimpy
Graduate Fellowship Program 70000.0
Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TAWHIDI, Zoya
Graduate Fellowship Program 70000.0
Monovalent anti-FcγRI strategy in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TUNDIDOR, Yaima
Postdoctoral Fellowship Program 162400.0
Novel techniques in transfusion medicine: Advancing clinical investigations and discovering new ligands of platelets Principal Investigator: BECKETT, Andrew

Co-Investigator(s) / Trainee: SHOARA, Aron
Postdoctoral Fellowship Program 164200.0
Demonstration of genetic blood group transition in patients undergoing ABO-mismatched allogeneic hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus – Full Study Principal Investigator: MCGINNIS, ERIC

Co-Investigator(s) / Trainee: SHIH, Andrew, WANG, Xiu Qing, STUBBINS, Ryan, HUDOBA, Monika, PETRASZKO, Tanya
Blood Efficiency Accelerator Program 30000.0
Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) Principal Investigator: MACK, Johnathan

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell
Blood Efficiency Accelerator Program 26385.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: GABARIN, Nadia
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Establishing national best practices for out-of-hospital blood transfusion: A collaboration of the Canadian Prehospital and Transport Transfusion (CAN-PATT) network Principal Investigator: NOLAN, Brodie

Co-Investigator(s) / Trainee: TROJANOWSKI, Jan, SHIH, Andrew, GREENE, Adam, EVANS, Rob, MULVEY, Jamin, CHANG, Eddie, NAHIRNIAK, Susan, PEARSON, Dallas, PROKOPCHUK-GAUK, Oksana, MARTIN, Doug, MUSUKA, Charles, SEIDL, Cindy, PEDDLE, Michael, LIN, Yulia, SMITH, Justin, MACDONALD, Scott, RICHARDS, Lindsay, FARRELL, Michael, KHANDELWAL, Aditi, CALLUM, Jeannie
Blood Efficiency Accelerator Program 30000.0
Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana
Postdoctoral Fellowship Program 162400.0
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Fc receptor blockade in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery
Intramural Research Grant Program 400000.0
Small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi P.
Intramural Research Grant Program 399130.0
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NAZY, Ishac
Intramural Research Grant Program 274854.0
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy
Intramural Research Grant Program 200000.0
A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) Principal Investigator: BARTOSZKO, Justyna

Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly
Intramural Research Grant Program 242617.0
Modified platelet storage containers to improve quality during storage Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas
Graduate Fellowship Program 52000.0
Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system Principal Investigator: GOLDMAN, Mindy

Co-Investigator(s) / Trainee: VESNAVER, Elisabeth
CIHR Health System Impact Fellowship 108500.0
Preservation of red blood cells by the novel isochoric oil-sealing supercooling system Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: ZHAO, Yuanheng
Postdoctoral Fellowship Program 167000.0
Generation of a coagulation factor-based thrombotic agent Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: WITT, Alexandra
Graduate Fellowship Program 52000.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0
Options for increasing plasma supply in Canada: A health economic preference and modelling study Principal Investigator: HOLLOWAY, Kelly

Co-Investigator(s) / Trainee: KENNEDY, Kevin
CIHR Health System Impact Fellowship 108500.0
Defining the stem cell regulatory functions of GAS6 and FTO Principal Investigator: MAGANTI, Harinad

Co-Investigator(s) / Trainee: PASALA, Ajay
Graduate Fellowship Program 52000.0
Assessing the relationship between red blood cell deformability and transfusion lifetime Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: LAMOUREUX, Erik
Graduate Fellowship Program 52000.0
Addressing racial disparity in blood, stem cell, and organ and tissue donor pools Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: OKONOFUA, Sylvia, YAN, Matthew, KHANDELWAL, Aditi, PENDERGRAST, Jacob, LEEIES, Murdoch, TINGA, Biba, HAW, Jennie, JAGELAVICIUTE, Gabriela, ROSENFELD, Aaron, KHANOLKAR, Rutvij, SEGALL, Romy, BELLINI, Jonathan, MORAKINYO, Tobi, AGYEPONG, Revée
BloodTechNet Award Program 34150.0
Improving blood product quality Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo
Intramural Research Grant Program 304462.0
The pan-Canadian immunoglobulin database: Enabling utilization reporting and personalized treatment using data mining techniques for immunoglobulin Principal Investigator: LI, Na

Co-Investigator(s) / Trainee: DOWN, Douglas, CHIANG, Fei, LEE, Joon, HEDDLE, Nancy, ARNOLD, Donald, CALLUM, Jeannie, SIDHU, Davinder, BARTY, Rebecca
Kenneth J. Fyke Award Program 100000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: VANDERMEULEN, Heather
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Optimizing Pre-Chemotherapy Anemia in Gynecologic Oncology (OPRA-2): A quality improvement initiative Principal Investigator: VICUS, Danielle

Co-Investigator(s) / Trainee: SPÉNARD, Elisabeth, LIN, Yulia, KHANDELWAL, Aditi, TANO, Ruby, JADUNANDAN, Saudia, KNIGHT, Dawn
Blood Efficiency Accelerator Program 30000.0
RBC hemolysis and cellular effector mechanisms (RHANCEM) Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong
Intramural Research Grant Program 399927.3
Identifying biomarkers for Staphylococcus aureus contamination of platelet component Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: CHI, Sylvia Ighem
Postdoctoral Fellowship Program 150000.0
Mechanisms of erythrocyte antibody-mediated immune suppression Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, SEMPLE, John
Intramural Research Grant Program 400000.0
IVIG utilization and its impact on platelet count in pregnant women with moderate thrombocytopenia Principal Investigator: KHALIFE, Roy

Co-Investigator(s) / Trainee: TINMOUTH, Alan, EL-CHAAR, Darine, MACK, Jonathan, KAROVITCH, Alan, FERGUSSON, Dean, WEBERT, Kathryn
Blood Efficiency Accelerator Program 22217.3
Donor factors and product quality Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa
Graduate Fellowship Program 122000.0
Mechanisms of anti-αIIb mediated miscarriage in fetal and neonatal alloimmune thrombocytopenia Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: CHEN, Zi Yan
Graduate Fellowship Program 52000.0
Perioperative transfusion threshold : A population-based observational study Principal Investigator: FERGUSSON, Dean

Co-Investigator(s) / Trainee: VERRET, Michael
Graduate Fellowship Program 52000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: TORDON, Bryan
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0