Our Research Publications

Updated November 2023

Title Authors Year Sort ascending Journal Link to Article Intended Audience Purpose
Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D 2016 BMJ Open Health care providers Clinical research
Outbreak of acute hepatitis B virus infection associated with exposure to acupuncture Rempel S, Murti M, Buxton J, Stephens W, Watterson M, Andonov A, Fung C, Ramler G, Bigham M, Lem M 2016 Canada Communicable Disease Report Health care providers Clinical research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep Researchers Basic research
Determining recruiting strategies for an adult stem cell registry Blake JT, McTaggart K, Killeen D 2016 Oper Res Health Care Blood operators New or improved product or process
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O'Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS 2016 Lancet Researchers Clinical research
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN 2016 ACS Omega Researchers Basic research
Development of standard definitions for surveillance of complications related to blood donation Goldman M, Land K, Robillard P, Wiersum-Osselton J 2016 Vox Sang Blood operators Benchmarking and standard setting
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion Researchers Other
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev Researchers Clinical research
ResearchUnit: Data mining 2: digging for deeper understanding of donors and transfusion outcome Fergusson DA, Acker J 2016 Blood.ca website Other Other
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun Researchers Basic research
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL 2016 BMJ Open Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife Researchers Clinical research
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials Researchers Basic research
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases Webert K, Kelton J 2016 Aspirin and related drugs Health care providers Clinical research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang Researchers Basic research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood Researchers Clinical research
Using simulation for strategic blood supply chain design in the Canadian prairies Blake J, McTaggart K 2016 Proceedings of the 6th International Conference on SIMULTECH Blood operators New or improved product or process
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang Researchers Basic research
Current trends in clinical studies of allogeneic hematopoietic stem cell transplantation Pilon S, Jedrysiak D, Sheppard D, Bredeson CN, Tay J, Allan DS 2015 Biol Blood Marrow Transplant Health care providers Clinical research
Epigenetic regulation of endothelial-cell-mediated vascular repair Fraineau S, Palii CG, Allan DS, Brand M 2015 FEBS J Researchers Other
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution Johnson L, Schubert P, Tan S, Devine DV, Marks DC 2015 Transfusion Researchers Basic research
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF 2015 Appl Spectrosc Researchers Basic research
How do I interpret a p value? O'Brien SF, Osmond L, Yi Q-L 2015 Transfusion Researchers Other
Megakaryopoiesis and ex vivo differentiation of stem cells into megakaryocytes and platelets Pineault N, Boisjoli GJ 2015 ISBT Sci Ser Researchers Basic research
Recommendations for standardization of laboratory testing for drug-induced immune thrombocytopenia: communication from the SSC of the ISTH Arnold DM, Curtis BR, Bakchoul T, for the Subcommittee on Platelet Immunology 2015 J Thromb Haemost Health care providers Benchmarking and standard setting
Fatal false-negative transfusion infection involving a buffy coat platelet pool contaminated with biofilm-positive Staphylococcus epidermidis: a case report Kou Y, Pagotto F, Hannach B, Ramirez-Arcos S 2015 Transfusion Health care providers Clinical research
Microfluidic deformability analysis of the red cell storage lesion Matthews K, Myrand-Lapierre M-E, Ang RR, Duffy SP, Scott MD, Ma H 2015 J Biomech Researchers New or improved product or process
Outcomes of both abbreviated hyper-CVAD induction followed by autologous hematopoietic cell transplantation and conventional chemotherapy for mantle cell lymphoma: a 10-year single-centre experience with literature review Alwasaidi TA, Hamadah A, Altouri S, Tay J, McDiarmid S, Faught C, Allan D, Huebsch L, Bredeson C, Bence-Bruckler I 2015 Cancer Med Health care providers Clinical research
ResearchUnit: Making the cut: protein breakdown in platelets during storage Serrano K 2015 Blood.ca website Other Other
Surveillance Report 2015 O'Brien SF 2015 Blood.ca website Other Other
Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer Siren EM, Singh S, Kluger R 2015 Org Biomol Chem Researchers Basic research
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS Researchers Basic research
Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis Shehata N, Forster AJ, Lawrence N, Ducharme R, Fergusson DA, Chassé M, Rothwell DM, Hébert PC, Tinmouth AT, Wilson K 2015 PLoS One Health care providers Clinical research
A phase-II sequential case-series study of all patients presenting to four plasma exchange centres with presumed relapsed/refractory thrombotic thrombocytopenic purpura treated with rituximab Clark WF, Rock G, Barth D, Arnold DM, Webert KE, Yenson PR, Kelton JG, Li L, Foley SR, members of the Canadian Apheresis G 2015 Br J Haematol Health care providers Clinical research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res Researchers Basic research
Effect of a thrombopoietin receptor agonist on use of intravenous immune globulin in patients with immune thrombocytopenia Zeller MP, Heddle NM, Kelton JG, Hamilton K, Wang G, Sholapur N, Carruthers J, Hsia C, Blais N, Toltl L, Hamm C, Pearson M-A, Arnold DM 2015 Transfusion Health care providers Clinical research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med Researchers Basic research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets Researchers Basic research
Improved Prediction of CD34+ Cell Yield before Peripheral Blood Hematopoietic Progenitor Cell Collection Using a Modified Target Value–Tailored Approach Sheppard D, Tay J, Palmer D, Xenocostas A, Doulaverakis C, Huebsch L, McDiarmid S, Tinmouth A, Mallick R, Martin L, Birch P, Hamelin L, Allan D, Bredeson C 2015 Biol Blood Marrow Transplant Health care providers New or improved product or process
Plasma and Plasma Protein Product Transfusion: A Canadian Blood Services Centre for Innovation Symposium Zeller MP, Al-Habsi KS, Golder M, Walsh GM, Sheffield WP 2015 Transfus Med Rev Health care providers Other
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J Researchers New or improved product or process
BK virus prophylaxis with levofloxacin--reply Gill JS, Knoll GA, Humar A 2015 JAMA Other Other
Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum Chasse M, McIntyre L, Tinmouth A, Acker J, English SW, Knoll G, Forster A, Shehata N, Wilson K, van Walraven C, Ducharme R, Fergusson DA 2015 BMJ Open Researchers Other
Determining the Volume of Additive Solution and Residual Plasma in Whole Blood Filtered and Buffy Coat Processed Red Cell Concentrates Jordan A, Acker J 2015 Transfus Med Hemother Researchers New or improved product or process
Maternal anti-platelet beta-3 integrins impair angiogenesis and cause intracranial hemorrhage Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai W-S, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen X-Y, Skogen B, Adamson SL, Freedman J, Ni H 2015 J Clin Invest Researchers Basic research
Intermittent bacteremia detected in an asymptomatic apheresis platelet donor with repeat positive culture for Escherichia coli: a case report Ramirez-Arcos S, Alport T, Goldman M 2015 Transfusion Blood operators Clinical research
Platelets and platelet alloantigens: lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia Vadasz B, Chen P, Yougbare I, Zdravic D, Li J, Li C, Carrim N, Ni H 2015 Genes Dis Researchers Other
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res Researchers Basic research