Our Funded Research Projects

Updated September 2023

Title Principal Investigator / Supervisor Program Project Start Date Sort descending Project End Date Total $ Awarded
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator: ENGLISH, Shane

Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program $157,172.00
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program $317,469.00
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee: KUEBLER, Wolfgang M.
Canadian Blood Services-CIHR Partnership Operating Grant Program $398,982.00
Myocardial Ischemia and Transfusion. The MINT rollover trial Principal Investigator: HEBERT, Paul

Co-Investigator(s) / Trainee: CARSON, Jeffrey L., DEVEREAUX, Philip J., EIKELBOOM, John W., FERGUSSON, Dean A., GOODMAN, Shaun G. , MCALISTER, Finlay A. , TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program $140,210.00
Polymer-based manufacturing tolerogenic miRNA-based therapeutics Principal Investigator: SCOTT, Mark

Co-Investigator(s) / Trainee: HORWITZ, Marc S.
Canadian Blood Services-CIHR Partnership Operating Grant Program $491,125.00
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator: EMERIAUD, Guillaume

Co-Investigator(s) / Trainee: DU PONT-THIBIDEAU, Genevieve, FONTELA, Patricia S. , GAUVIN, France, GILFOYLE, Elaine, HUTCHISON, James S., LACROIX, Jacques, MENON, Kusum, ROBITAILLE, Nancy, TINMOUTH, Alan T., TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program $477,651.00
Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: CHASSE, Michael, FERGUSSON, Dean A., GOLDMAN, Mindy R., O'BRIEN, Sheila F., SPRAGUE, Ann, van WALRAVEN, Carl, WALKER, Mark C., WILSON, Kumanan
Canadian Blood Services-CIHR Partnership Operating Grant Program $135,657.00
Study of the mechanisms implicated in platelets microparticle internalization by blood cells Principal Investigator: BOILARD, Eric

Co-Investigator(s) / Trainee: MARCOUX, Genevieve
Graduate Fellowship Program $104,000.00
Recombinant Fc multimers to replace IVIG Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: LEWIS, Bonnie
Graduate Fellowship Program $104,000.00
DNA aptamers for detection of red blood cells destined for rapid post-transfusion clearance Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: DONKOR, David
Postdoctoral Fellowship Program $150,000.00
Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu
Intramural Research Grant Program $400,000.00
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator: GRUBEN, Vanessa

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program $150,000.00
Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo
Intramural Research Grant Program $250,660.00
Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike
Graduate Fellowship Program $52,000.00
Red cell genotyping using buccal swab DNA Principal Investigator: BERARDI, Philip

Co-Investigator(s) / Trainee: GOLDMAN, Mindy R., HANNON, Judith, CLARKE, Gwen, LIWSKI, Robert
Small Project Funding Program $15,000.00
Platelet desialylation: novel mechanism of platelet clearance and immune tolerance Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LI, June
Graduate Fellowship Program $104,000.00
Incidence of intracranial hemorrhage in pediatric oncology patients Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee:
Small Project Funding Program $15,000.00
Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: POISSON, Jessica
Graduate Fellowship Program $82,000.00
Podcast for FNAIT and ICTMG red cell specifications for hemoglobinopathies guidelines Principal Investigator: SHEHATA, Nadine

Co-Investigator(s) / Trainee:
BloodTechNet Award Program $6,200.00
The Stem Cell Club: educating medical and nursing students to develop professional skills Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee:
BloodTechNet Award Program $24,458.00
Social media for knowledge translation and education 3 (SoMe-KTE3): Transfusion, thrombosis, and hemostasis Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: CHAN, Teresa, DE WIT, Kristin, BHAGIRATH, Vinai, YEH, Calvin, CASTELLUCI, Lana, ELAHIE, Allahna, HEDDLE, Nancy, THOMA, Brent
BloodTechNet Award Program $30,000.00
National evaluation of platelet transport bags to reduce wastage Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: CALLUM, Jeannie, LIN, Yulia, LIEBERMAN, Lani, PENDERGRAST, Jacob, CSERTI-GAZDEWICH, Christine
Small Project Funding Program $9,740.00
Use of red blood cell antigen genotyping to assess RhD diversity in sickle cell disease patients Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: BERARDI, Philip, CLARKE, Gwen, HANNON, Judith, HEDDLE, Nancy, VERHOVSEK, Madeleine
Small Project Funding Program $15,000.00
ROTEM-guided transfusion protocols - impact on the manufacturer Principal Investigator: TRUDEAU, Jacqueline

Co-Investigator(s) / Trainee: PETRASZKO, Tanya, LI, Cecilia
Small Project Funding Program $15,000.00
Neonatal outcomes after transfusion of ABO non-identical blood (Neo-ABO) Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: HEDDLE, Nancy, COOK, Richard J., FUSCH, Christoph
Small Project Funding Program $14,988.68
Pre-transfusion furosemide for TACO Principal Investigator: SKEATE, Robert

Co-Investigator(s) / Trainee: CALLUM, Jeannie
Small Project Funding Program $15,000.00
Human monoclonal CD44 antibodies as potential IVIg replacements Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $336,000.00
Improving pathogen inactivation: the dengue virus-induced platelet proteome Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu
Graduate Fellowship Program $104,000.00
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $224,417.00
Data sharing with CBMTG registry Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: PAULSON, Kristjan
Small Project Funding Program $15,000.00
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program $332,942.00
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program $101,200.00
Studying and alleviating the effects of platelet microparticles induced by pathogen reduction of platelet concentrates Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: LAUGIER, Jonathan
Graduate Fellowship Program $52,000.00
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NORRIS, Peter
Graduate Fellowship Program $112,333.33
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: MOON, Haisle
Graduate Fellowship Program $90,333.33
An innovative digital strategy for dissemination of Choosing Wisely Canada guidelines in transfusion medicine Principal Investigator: CAMPBELL, Clinton

Co-Investigator(s) / Trainee: LABRECQUE, Suzanne, LABELLE, Peter, AL-JEDANI, Hanadi, SADEK, Irene, KAHWASH, Eiad
BloodTechNet Award Program $25,000.00
Synthesis of carbohydrate derivatives for the improvement of red blood cell storage Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MEYER, Julia
Graduate Fellowship Program $79,500.00
PID (Primary Immune Deficiency) Toolkit App Principal Investigator: DARNEL, Susanna

Co-Investigator(s) / Trainee: LI, Cecilia, BEAUCHAMP, Aimee, MORRISON, Doug, DALLAS, Karen, MICHAAN, Jack, TAVASZI, Alina, DENESIN, Pam, FUNG, Rene, British Columbia Primary Immune Deficiency (PID) Group Members
BloodTechNet Award Program $25,000.00
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program $398,871.00
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program $100,000.00
Expanding treatment options for inflammatory bowel disease: A novel mechanism of antibody-based immunotherapy Principal Investigator: SLY, Laura

Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program $408,540.60
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program $471,393.00
Assessing unintentional creation of bias against MSM as a function of exposure to blood donor screening questionnaire and assessing sexual behaviour risk factors of those successfully passing blood donor screening Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee:
MSM Research Grant Program $56,000.00
McMaster Centre for Transfusion Research Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,303,333.50
University of Toronto QUEST Research Program Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,290,733.50
Assessing alternative Canadian Blood Services blood donor deferral screening policies for men who have sex with men Principal Investigator: BRENNAN, David

Co-Investigator(s) / Trainee: ADAM, Barry, HART, Trevor, LACHOWSKY, Nathan, GRACE, Daniel
MSM Research Grant Program $60,000.00
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program $50,000.00
Process evaluation of the Canadian Blood Services' cord blood bank: managerial and donor perspectives Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: HAW, Jennie
CIHR Health System Impact Fellowship $46,500.00
Operational impact of individual risk assessment options Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: ROBILLARD, Pierre, GOLDMAN, Mindy, MYHAL, Geneviève
MSM Research Grant Program $168,000.00
Attitudes, behaviours, and acceptability related to current and future blood donation policy: A qualitative study of gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montréal Principal Investigator: GRACE, Daniel

Co-Investigator(s) / Trainee: HART, Trevor, LAMBERT, Gilles, COX, Joseph , ADAM, Barry , BRENNAN, David , LACHOWSKY, Nathan, MOORE, David
MSM Research Grant Program $60,000.00