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A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver

Principal Investigator / Supervisor: 
LACHOWSKY, Nathan
Co-Investigator(s) / Trainee: 
HOGG, Robert
MOORE, David
ROTH, Eric
ARMSTRONG, Heather
Institution: 
University of Victoria
Province: 
British Columbia
Project Start Date: 
August 1, 2017
Project End Date: 
July 31, 2018
Summary: 
Our team proposes a secondary data analysis of the Momentum Health Study (momentumstudy.ca), an ongoing prospective bio-behavioural cohort study of 698 men who have sex with men (MSM) in Metro Vancouver that began recruitment in 2012. Our main objectives are to: 1) calculate the biological incidence rate of HIV, hepatitis C virus (HCV) and syphilis infection among MSM who report (or do not report) certain behaviours to identify sub-groups with zero or very low risk of infection; and 2) evaluate the stability of individual risk-based factors (behaviour based) over time within MSM to inform time period windows for deferral criteria. To date, 551 HIV-negative participants have contributed a median follow-up time of 2.98 years, providing biological specimens for HIV, HCV and syphilis testing at each visit. We will identify a “low-risk” sub-group of sexually-active MSM who could be eligible to donate and would not introduce any additional risk to the blood supply. To do so, we will identify a limited set of necessary behavioural questions to develop an individual risk assessment donor policy, potentially implementable as “gender-blind”. Given our extensive dataset, we will also provide the necessary parameter estimates required to evaluate whether there would be any increased risk introduced to the blood supply if the current deferral policy were changed.
Total Amount Awarded: 
$50,000
Program: 
MSM Research Grant Program - Small Project

Projects summaries are contributed by investigators who receive financial support from Canadian Blood Services. The summaries are intended to inform the public of the types of research projects that are supported by our organization. The information described in project summaries should not be considered as recommendation for clinical treatment and diagnosis.