Improving cord blood product quality

The issue

Cord blood (CB) units are stored frozen at -196°C until they are required for transplantation.  Protocols for storage or shipping of frozen CB units can result in transient warming of the units above critical subzero temperatures, which may impact cell viability and efficacy. Protocols for thawing CB units prior to transplantation are also critical in ensuring product efficacy. Canadian Blood Services examined how different protocols for handling and thawing affected CB quality. 

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